Protein Info for Xcc-8004.4554.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01135: glutamine-fructose-6-phosphate transaminase (isomerizing)
  • amino acids 2 to 609 (608 residues), 859.9 bits, E=5.4e-263
• PF13522: GATase_6
  • amino acids 63 to 183 (121 residues), 72.8 bits, E=4.2e-24
• PF13537: GATase_7
  • amino acids 81 to 197 (117 residues), 60.3 bits, E=2.7e-20
• PF01380: SIS
  • amino acids 291 to 416 (126 residues), 97.8 bits, E=6.9e-32
  • amino acids 463 to 591 (129 residues), 83.1 bits, E=2.3e-27

Best Hits

Swiss-Prot: 100% identical to GLMS_XANCP: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (glmS) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K00820, glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC: 2.6.1.16] (inferred from 100% identity to xcb:XC_3663)

Predicted SEED Role

"Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)" in subsystem Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 2.6.1.16)

MetaCyc Pathways

• O-antigen building blocks biosynthesis (E. coli) (11/11 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis I (5/5 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis II (4/6 steps found)
• chitin biosynthesis (6/9 steps found)
• UDP-N-acetyl-D-galactosamine biosynthesis III (2/6 steps found)
• CMP-legionaminate biosynthesis I (2/10 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (13/33 steps found)
• superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis (6/24 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Glutamate metabolism
• Nucleotide sugars metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.16

Use Curated BLAST to search for 2.6.1.16

Sequence Analysis Tools

See A0A0H2XB11 at UniProt or InterPro

Protein Sequence (609 amino acids)

>Xcc-8004.4554.1 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) (Xanthomonas campestris pv. campestris strain 8004)
MCGIVGAIAGRDVVPVLIEGLKRLEYRGYDSSGIAVLDGTQVRRVRRTGRVAEMAQAAQA
EQFGATLGIGHTRWATHGGVTEANAHPHISAGVALVHNGIIENHEEQREKLRALGYTFES
QTDTEVIAHLIHHHLADAGDLLSALQRTVKELTGAYALAVMSQAEQERFVCARMGCPLLI
GVGEGENFVASDVSAIVQATRQVIFLEEGDTAELRRDGVRVFDASDAAVERPLHLSDVSL
ASLELGPFRHFMQKEIHEQPRALADTIEAAIDAKGFPASLFGPTADAVLRDIEGVQILAC
GTSYYAGLTARYWIEAIAGLPCSVEIASEYRYRAAYANPKHLIVTISQSGETLDTMEALK
YAKSLGHLHTLSICNVPESAIPRASELVCYTRAGAEIGVASTKAFTTQLAVLFQLTMVLG
KLQGRISDSEEADYLEQLRFLPGSVQHALNLEPQIMAWAERFSPKENALFLGRGLHYPIA
LEGALKLKEISYIHAEAYPAGELKHGPLALVDATMPVVVIAPNDRLLEKVKSNMQEVRAR
GGELFVFADQDSHFSESDGVHVIRTPRHAGVLSPVIHTIPVQLLAYHTALARGTDVDKPR
NLAKSVTVE