Protein Info for Xcc-8004.4379.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 886 transmembrane" amino acids 394 to 413 (20 residues), see Phobius details amino acids 424 to 458 (35 residues), see Phobius details amino acids 468 to 490 (23 residues), see Phobius details PF02702: KdpD" amino acids 21 to 229 (209 residues), 306.3 bits, see alignment E=2.4e-95 PF00582: Usp" amino acids 250 to 361 (112 residues), 29.4 bits, see alignment E=2.7e-10 PF13493: DUF4118" amino acids 397 to 499 (103 residues), 83.4 bits, see alignment E=2.3e-27 PF00512: HisKA" amino acids 653 to 719 (67 residues), 49.4 bits, see alignment 9.4e-17 PF02518: HATPase_c" amino acids 768 to 874 (107 residues), 82.2 bits, see alignment E=9.3e-27

Best Hits

KEGG orthology group: K07646, two-component system, OmpR family, sensor histidine kinase KdpD [EC: 2.7.13.3] (inferred from 100% identity to xcb:XC_3529)

Predicted SEED Role

"Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-)" in subsystem Potassium homeostasis (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2XAL3 at UniProt or InterPro

Protein Sequence (886 amino acids)

>Xcc-8004.4379.1 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) (Xanthomonas campestris pv. campestris strain 8004)
MSDARTQQADALIGELQREHGGRLTVFLGAAPGVGKTYAMLSRARERLRQGVDVVAGVVE
THGRSETAALLDGVPLLPRVQVSYQGHALEELALDALLARKPQLALIDELAHRNVPGSRH
ERRWQDTVELLDAGIDVYTTVNIQHLESLNDIVLRITGVRVSETVPDAVFDRLRDIVLVD
LPPRELIERLQQGKVYLPEQASQALQAFFSPSNLTALRELAMQTAADRVDSDLRDTQAAR
GLPGTAALRRHVVVAIDGRGSSDYLVRVARRLSERRDAPWTVVTVQTRTVADAAWQLEID
RAFALTRRLGGDTALLHGANVADALLDFASQNGVSTLVLGRTRERPLARMFNRTLTQQLL
QRGAHYELVIVSSGDARARARQRWRNPGQWLQRYDLAYAAIAAAAAVAVAWVIQRWTDID
DLSMVFIVAVVLVASRTRMAAAVIAALLSFVAYNFFFIEPRFTLHISARQGVVTVCLFLI
AALVAGRLASRLRSQVLALRAANAHANALQALARQLSTAADLGQVLEAGRRALASALDAE
VWLRLEQCESEAPTSFSALDRNAADWTQRHGQPAGRFTDTLAGAQWWCLPVRHERGTLGV
AALRFRQQLQRPGLEQRRLAEAMVEDIGQAALRTRLVADLEGARVSGETERLRSALLSSV
SHDLRSPLASMIGSASSLAEYGEAMDATDRRSLLETIQLEGERLDRYIQNLLDMTRLGHT
GLTLKRDWIGVDELIGSATRRLQRYQPQVRLQLDLAPELPAIWVHPALVEQAIFNVLENA
AKFSPPGVAVTVQARLQSGALQIEIGDQGPGIPEDERARIFDMFYSVERGDRGRHGTGLG
LTICQGMIGAHGGSVEALAGPHGHGTTIRITLPLLVPAASPRPDAD