Protein Info for Xcc-8004.3955.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: HflK protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 transmembrane" amino acids 48 to 68 (21 residues), see Phobius details TIGR01933: HflK protein" amino acids 65 to 321 (257 residues), 328.3 bits, see alignment E=1.7e-102 PF01145: Band_7" amino acids 68 to 239 (172 residues), 126.4 bits, see alignment E=6.4e-41

Best Hits

Swiss-Prot: 37% identical to HFLK_VIBCH: Protein HflK (hflK) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K04088, membrane protease subunit HflK [EC: 3.4.-.-] (inferred from 100% identity to xcb:XC_3196)

Predicted SEED Role

"HflK protein" in subsystem Hfl operon

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.-.-

Use Curated BLAST to search for 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2XBT5 at UniProt or InterPro

Protein Sequence (380 amino acids)

>Xcc-8004.3955.1 HflK protein (Xanthomonas campestris pv. campestris strain 8004)
MAWNTPGNKGGDGPDPNRRRSWGPRGGGNGGGWGNLPAPLKELFDGGVWRWVLIAVVLMV
LFSSFQLIGEQQRGVVLRFGQFSRILQPGPSFKLPWPIESVRKVNATEIKTFSNQVPVLT
RDENIVNVSLNVQYQISDPRKYLFGSRNADLVLEQAAQSAVREQVGRSDLNTVLNNRGPL
AIASKDRLQAALNAYNTGLSVTGVTLPDARPPEEVKPAFDEVNGAQQVRERLINEAQAYA
AKVVPEARGQGARTRTGAEGYKQAVISKAEGDADRFTLLQEQYAGAPDVTRKRLWLETVQ
KVLSENRKVIGSDGRQVIYVPLPADAGKSGNAGTATGNGSTPSMVPQDVLLNPPQGNGGS
AEGIRNPERGPRPTGREGTE