Protein Info for Xcc-8004.391.1 in Xanthomonas campestris pv. campestris strain 8004
Annotation: NAD-dependent protein deacetylase of SIR2 family
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to NPD_XANC8: NAD-dependent protein deacetylase (cobB) from Xanthomonas campestris pv. campestris (strain 8004)
KEGG orthology group: None (inferred from 100% identity to xcb:XC_0318)Predicted SEED Role
"NAD-dependent protein deacetylase of SIR2 family" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate or Redox-dependent regulation of nucleus processes
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q4UZX0 at UniProt or InterPro
Protein Sequence (293 amino acids)
>Xcc-8004.391.1 NAD-dependent protein deacetylase of SIR2 family (Xanthomonas campestris pv. campestris strain 8004) MTVAITQTGPALQEFVERHQRLFVLSGAGCSTDSGIPDYRDLQGGWKRPQPVTFQAFMGE LSTRQRYWARSLVGWPRFGLARPNATHHALAALEARGQLELLLTQNVDRLHQAAGSQAVI DLHGRLDVVRCMGCEQRMPRTEFQLLLERDNPGWADLEAAQAPDGDADLDNVAFDNFVVP ACPACGGVLKPDVVFFGENVPRERVERAFAHLQAADAVLVVGSSLMVYSGFRFVQAAARA GLPIAALNFGRTRADDLLSLKVEQSCAQALAFLQQPPDPLHTATARYHSARSA