Protein Info for Xcc-8004.3817.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01433: ubiquinol oxidase, subunit II
  • amino acids 52 to 273 (222 residues), 376.8 bits, E=1.6e-117
• PF00116: COX2
  • amino acids 184 to 258 (75 residues), 29.1 bits, E=8.3e-11
• PF06481: COX_ARM
  • amino acids 273 to 320 (48 residues), 56.6 bits, 1.9e-19

Best Hits

Swiss-Prot: 60% identical to CYOA_PSEAE: Cytochrome bo(3) ubiquinol oxidase subunit 2 (cyoA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02297, cytochrome o ubiquinol oxidase subunit II [EC: 1.10.3.-] (inferred from 100% identity to xca:xccb100_3180)

MetaCyc: 59% identical to cytochrome bo terminal oxidase subunit II (Pseudomonas putida KT2440)
RXN0-5268 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

• NADH to cytochrome bo oxidase electron transfer I (2/2 steps found)
• glycerol-3-phosphate to cytochrome bo oxidase electron transfer (2/2 steps found)
• pyruvate to cytochrome bo oxidase electron transfer (2/2 steps found)
• succinate to cytochrome bo oxidase electron transfer (2/2 steps found)
• D-lactate to cytochrome bo oxidase electron transfer (1/2 steps found)
• NADH to cytochrome bo oxidase electron transfer II (1/2 steps found)
• proline to cytochrome bo oxidase electron transfer (1/2 steps found)

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

See A0A0H2X9W6 at UniProt or InterPro

Protein Sequence (349 amino acids)

>Xcc-8004.3817.1 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) (Xanthomonas campestris pv. campestris strain 8004)
VSSIWAAISTGSGLFKTPLADQTNEAGVPSHLDRPMIPLKHLGRVLRPGLMLPFLLLAGC
NSAILNPKGQIGHDEKQLLITSVVLMLIVVIPVIVMAIAFAWKYRASNTKARYEPDWSHS
TAIEVVVWSIPCVIILVLAVLTWRSSHALDPYRPLDSDIKPINIEAVSLDWKWMFIYPDQ
GIATVNEIAFPVHAPLNFKITSDTVMNAFFIPHLGTMIYSMAGMETKLHLVANEPGEYFG
LSSNYSGHGFSKMSFVARATDQAGFEAWVAKVKASPKALDAAEYQALAANRNDKEQYPVT
YYSSVPDGMFRSLIDKYMMGSHHSESHAGGKAKVVEPFAMCTSETTDVR