Protein Info for Xcc-8004.3720.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Type III secretion outermembrane pore forming protein (YscC,MxiD,HrcC, InvG)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 605 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF03958: Secretin_N" amino acids 120 to 181 (62 residues), 28.6 bits, see alignment E=2e-10 amino acids 187 to 364 (178 residues), 47.9 bits, see alignment E=2e-16 TIGR02516: type III secretion outer membrane pore, YscC/HrcC family" amino acids 320 to 604 (285 residues), 359.7 bits, see alignment E=9.8e-112 PF00263: Secretin" amino acids 446 to 603 (158 residues), 132.5 bits, see alignment E=1.8e-42

Best Hits

Swiss-Prot: 85% identical to HRPA1_XANEU: Hypersensitivity response secretion protein HrpA1 (hrpA1) from Xanthomonas euvesicatoria

KEGG orthology group: K03219, type III secretion protein SctC (inferred from 100% identity to xcb:XC_3003)

Predicted SEED Role

"Type III secretion outermembrane pore forming protein (YscC,MxiD,HrcC, InvG)" in subsystem Type III secretion systems, extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X9U6 at UniProt or InterPro

Protein Sequence (605 amino acids)

>Xcc-8004.3720.1 Type III secretion outermembrane pore forming protein (YscC,MxiD,HrcC, InvG) (Xanthomonas campestris pv. campestris strain 8004)
MAYACPPVHRHRRAPLAAALLLGLLPLLPPHANAASVPWHSRSFKYVADRKDLKEVLRDL
SASQSITTWISPEVTGTLSGKFEATPQKFLDDLSGTFGFVWYYDGSVLRIWGANETKNAT
LSLGAASTSALRDALARMRLDDPRFPVRYDETAHLAVVSGPPGYVDTVAAIAKQVEQVAR
QRDATEVQVFQLHYAQAADHTTRIGGQDIQVPGMASLLRNIYGVRGAPTAALPGPGANFG
RVQPIGGGSSNTFGNSGQRQSGGSGILGLPASWFGAGSPSERVPVSPPLPGSGNSANAPA
SVWPEMSQARRDAPLAVDAGSGGELASDAPVIEADPRTNGILIRDRPERMAAYGTLIQQL
DNRPKLLQIDATIIEIRDGALQDLGVDWRFHSRRVDVQTGDGRGGQLGYDGSLSGAAAAG
AAAPLGGTLTAVLGDAGRYLMTRVSALEQTNKAKIVSTPQVATLDNVEAVMDHKQQAFVR
VSGYASADLYNLSAGVSLRVLPSVVPGSPNGQMRLDVRIEDGQLGANTVDGIPVITSSEI
TTQAFVNEGQSLLIAGYASDTDQTDLNNVPGLSRIPLVGNLFKHRQQSGSRLQRLFLLTP
HIVSP