Protein Info for Xcc-8004.3544.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Methionine aminopeptidase (EC 3.4.11.18)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 307 TIGR00500: methionine aminopeptidase, type I" amino acids 53 to 299 (247 residues), 330.9 bits, see alignment E=2.5e-103 PF00557: Peptidase_M24" amino acids 61 to 291 (231 residues), 190.6 bits, see alignment E=1.6e-60

Best Hits

Swiss-Prot: 62% identical to MAP1_SALTI: Methionine aminopeptidase (map) from Salmonella typhi

KEGG orthology group: K01265, methionyl aminopeptidase [EC: 3.4.11.18] (inferred from 100% identity to xca:xccb100_2915)

MetaCyc: 61% identical to methionine aminopeptidase (Escherichia coli K-12 substr. MG1655)
Methionyl aminopeptidase. [EC: 3.4.11.18]

Predicted SEED Role

"Methionine aminopeptidase (EC 3.4.11.18)" (EC 3.4.11.18)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.18

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X9B5 at UniProt or InterPro

Protein Sequence (307 amino acids)

>Xcc-8004.3544.1 Methionine aminopeptidase (EC 3.4.11.18) (Xanthomonas campestris pv. campestris strain 8004)
MTPFHAVLTREDLRHNSGPLAPDFRRRARACRAKRGVIQIRSESAIIRHMSVNLKTKEEI
ELMRVAGRLAAEVLDVVAPHVKPGVTTAELDRICHDHIVNVQGTIPANVGYRGFPKSVCT
SVNNVICHGIPSAAKVLKEGDIVNIDVTVIKDGWHGDTSRMYYVGTPSVMAKRLVETTYE
AMWRGIRAVKPGATLGDVGHAIQKFAEAERFSVVRDYCGHGIGKVYHDEPQVMHYGRPGE
GLVLKPGMTFTIEPMINEGTYHHKTLPDGWTVVTKDRKLSAQWEHMVAVTEDGVDVLTLS
PNASAPA