Protein Info for Xcc-8004.3294.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Formiminoglutamic iminohydrolase (EC 3.5.3.13)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 PF22429: HutF_N" amino acids 7 to 48 (42 residues), 50.5 bits, see alignment 1.5e-17 TIGR02022: formiminoglutamate deiminase" amino acids 7 to 454 (448 residues), 694.9 bits, see alignment E=2.3e-213 PF01979: Amidohydro_1" amino acids 51 to 429 (379 residues), 84.8 bits, see alignment E=6.9e-28

Best Hits

KEGG orthology group: None (inferred from 99% identity to xca:xccb100_2679)

MetaCyc: 52% identical to formiminoglutamate deiminase subunit (Pseudomonas fluorescens)
Formimidoylglutamate deiminase. [EC: 3.5.3.13]

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2XAF1 at UniProt or InterPro

Protein Sequence (456 amino acids)

>Xcc-8004.3294.1 Formiminoglutamic iminohydrolase (EC 3.5.3.13) (Xanthomonas campestris pv. campestris strain 8004)
VADQAVQAVWAARALLPDGWASDVRITVAYGRIAAVQTEAMPAATDTRAEVLLPGLGNLH
SHAFQRGMAGLTEVGGRSGDSFWSWRELMYRFVDRLDPDSLQAIAEQAYVEMLEAGFTRV
GEFHYLHHSVSGAPYAQPAEMAERIVAAAAGTGIGLTLLPVFYAHSDFGGVPPNPAQRRL
IHDIDGFARLLSDCARSLAALPDAVLGLAPHSLRAVTPTQLAALVPLVDGPIHIHIAEQQ
REVEACLAWSGQRPVQWLYANAPVDARWCLVHATHVEAGKLDAIVKSGAVVGLCPITEAN
LGDGLFPMQAFASRGGRFGVGSDSNVLIDAAEELRLLEYGQRLQLRARNVLAPADTSSGR
WLYSSALAGAAQALGSGQPGICVGASADLLELDHTHPALLARTDDALLDSWLFAARAGAV
RHVWRAGQCVVRDGRHVARERVAARFAAVMQTLLHG