Protein Info for Xcc-8004.290.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: NAD(P)H steroid dehydrogenase-like protein in alkane synthesis cluster

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 336 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details PF04321: RmlD_sub_bind" amino acids 1 to 224 (224 residues), 48.6 bits, see alignment E=2.4e-16 PF05368: NmrA" amino acids 2 to 115 (114 residues), 37.1 bits, see alignment E=1.1e-12 PF02719: Polysacc_synt_2" amino acids 3 to 126 (124 residues), 35.5 bits, see alignment E=2.6e-12 PF01370: Epimerase" amino acids 3 to 218 (216 residues), 130.5 bits, see alignment E=2.8e-41 PF01073: 3Beta_HSD" amino acids 4 to 251 (248 residues), 168.8 bits, see alignment E=5.3e-53 PF16363: GDP_Man_Dehyd" amino acids 4 to 251 (248 residues), 52.7 bits, see alignment E=1.9e-17 PF13460: NAD_binding_10" amino acids 7 to 150 (144 residues), 59.4 bits, see alignment E=1.8e-19 PF07993: NAD_binding_4" amino acids 54 to 170 (117 residues), 50.3 bits, see alignment E=7.9e-17

Best Hits

Swiss-Prot: 100% identical to OLED_XANCP: 2-alkyl-3-oxoalkanoate reductase (oleD) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: None (inferred from 100% identity to xcc:XCC0219)

MetaCyc: 100% identical to 2-alkyl-3-oxo-fatty acid reductase monomer (Xanthomonas campestris)
RXN-18556 [EC: 1.1.1.412]

Predicted SEED Role

"NAD(P)H steroid dehydrogenase-like protein in alkane synthesis cluster"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.412

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X2L7 at UniProt or InterPro

Protein Sequence (336 amino acids)

>Xcc-8004.290.1 NAD(P)H steroid dehydrogenase-like protein in alkane synthesis cluster (Xanthomonas campestris pv. campestris strain 8004)
MKILVTGGGGFLGQALCRGLVARGHEVVSFQRGDYPVLHTLGVGQIRGDLADPQAVRHAL
AGIDAVFHNAAKAGAWGSYDSYHQANVVGTQNVLDACRANGVPRLIYTSTPSVTHRATNP
VEGLGADEVPYGEDLRAPYAATKAIAERAVLAANDAQLATVALRPRLIWGPGDNHLLPRL
AARARAGRLRMVGDGSNLVDSTYIDNAAQAHFDAFAHLAPGAACAGKAYFISNGEPLPMR
ELLNRLLAAVDAPAVTRSLSFKTAYRIGAVCETLWPLLRLPGEVPLTRFLVEQLCTPHWY
SMEPARRDFGYVPQISIEEGLQRLRSSSSRDISITR