Protein Info for Xcc-8004.2898.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Sensory/regulatory protein rpfC (EC 2.7.3.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 726 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details amino acids 51 to 72 (22 residues), see Phobius details amino acids 128 to 147 (20 residues), see Phobius details amino acids 153 to 172 (20 residues), see Phobius details PF00512: HisKA" amino acids 188 to 253 (66 residues), 74.5 bits, see alignment E=1.2e-24 PF02518: HATPase_c" amino acids 300 to 416 (117 residues), 90.3 bits, see alignment E=2.4e-29 PF00072: Response_reg" amino acids 465 to 577 (113 residues), 83.3 bits, see alignment E=2.9e-27 PF01627: Hpt" amino acids 624 to 699 (76 residues), 36.2 bits, see alignment E=1.2e-12

Best Hits

Swiss-Prot: 100% identical to RPFC_XANC8: Sensory/regulatory protein RpfC (rpfC) from Xanthomonas campestris pv. campestris (strain 8004)

KEGG orthology group: K10715, two-component system, sensor histidine kinase RpfC [EC: 2.7.13.3] (inferred from 100% identity to xcb:XC_2333)

Predicted SEED Role

"Sensory/regulatory protein rpfC (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P0C0F7 at UniProt or InterPro

Protein Sequence (726 amino acids)

>Xcc-8004.2898.1 Sensory/regulatory protein rpfC (EC 2.7.3.-) (Xanthomonas campestris pv. campestris strain 8004)
MKSPLPWLKRRLSGRADSEHAQNLIRIIITTLFISYLGWRYQHTHGDTLMATWLILVGEL
LVSLGLMVAILLRPQVSHTRRLIGMLLDYTCTGAIMAIQGEPASPLYAVCMWVTIGNGLR
YGSNYLRAATAMGSLCFLGAILISPYWKANPYLSWGLLLGLIAVPLYFDSLLRAMTRAVR
EARHANQAKSRFLANMSHEFRTPLNGLSGMTEVLATTRLDAEQKECLNTIQASARSLLSL
VEEVLDISAIEAGKIRIDRRDFSLREMIGSVNLILQPQARGRRLEYGTQVADDVPDLLKG
DTAHLRQVLLNLVGNAVKFTEHGHVLLRVTRVSGSAEDAVRLRFDVEDTGIGVPMDMRPR
LFEAFEQADVGLSRRYEGTGLGTTIAKGLVEAMGGSIGFKENQPSGSVFWFELPMAIGEP
LKSSTVRVPTGALVDAPEELESSNIIAFSNPFLRHRARVRSMRMLVADDHEANRMVLQRL
LEKAGHKVLCVNGAEQVLDAMAEEDYDAVIVDLHMPGMNGLDMLKQLRVMQASGMRYTPV
VVLSADVTPEAIRACEQAGARAFLAKPVLAAKLLDTLADLAVSTRQLATPATTVQVATSF
EGVLDSSVLDELAALGMGEEFERQFVRQCLDDAQNCVGDIERDGTCSDWEQLRESAHALR
GVASNLGLAQVASSGGELMRMADWQLQAEWRLRLSTLREQLKAGKDALDARVQGVKDGEC
SPRSNE