Protein Info for Xcc-8004.2889.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 760 TIGR00229: PAS domain S-box protein" amino acids 45 to 165 (121 residues), 71.1 bits, see alignment E=9.4e-24 PF13188: PAS_8" amino acids 47 to 90 (44 residues), 31.1 bits, see alignment 7.3e-11 PF00989: PAS" amino acids 48 to 158 (111 residues), 50.6 bits, see alignment E=8.5e-17 PF08448: PAS_4" amino acids 52 to 162 (111 residues), 60.3 bits, see alignment E=9.2e-20 PF13426: PAS_9" amino acids 57 to 160 (104 residues), 67.2 bits, see alignment E=6.3e-22 PF08447: PAS_3" amino acids 69 to 154 (86 residues), 31.2 bits, see alignment E=9.5e-11 PF13185: GAF_2" amino acids 180 to 321 (142 residues), 41.8 bits, see alignment E=5.7e-14 PF01590: GAF" amino acids 201 to 319 (119 residues), 45.1 bits, see alignment E=6.8e-15 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 332 to 491 (160 residues), 117.1 bits, see alignment E=6.5e-38 PF00990: GGDEF" amino acids 334 to 488 (155 residues), 140.6 bits, see alignment E=1.8e-44 PF00563: EAL" amino acids 510 to 746 (237 residues), 245.2 bits, see alignment E=2.8e-76

Best Hits

KEGG orthology group: None (inferred from 100% identity to xca:xccb100_2153)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X9P7 at UniProt or InterPro

Protein Sequence (760 amino acids)

>Xcc-8004.2889.1 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (Xanthomonas campestris pv. campestris strain 8004)
MTAPPPHPADPAADPGSPGSAAAGHAETPTQIDAMPGESASDTRSRLLAQALDGSSSAIL
ICDLQSRLLYANDGFERMFGYTEAELVGQRPSHVLTRALSDQTEVARIRERADALQQTQA
DLLVYRKDGTPLWISLNFNPIYDAQHNPSHYVAVLTDITETKMHEVLQHRVLEALVQERP
LIEVMTLICTEVERIAPEVLATVMSADNDGCLHSLAAPSLPPEYADAVNGLKIGPGAGAC
GTAAWRGRAVMVEDIANDPLFTHFRDLLLPMGLRACWSTPIRANSSRVLGTFALYYRSVR
RADAWHVKLTDLCQQLCTLALEREQIRQRVHQLAFYDALTGLPNRIMFSARAEQALTHAE
YAGEPAALMFINIDRFKLINDSQGHAAGDGLLRDIALRIGEQLTATAMLARLAGDEFALA
LPQCSAEQASATAERLLGTIAGPLPVGHMTVHPSASVGVAMFPEDGRDINILLRHADLAM
NRAKKEGGGRFRFFSADMNRMAQERVALEAELRQAIGRNQLQLHYQPQLLSQAPHALYGV
EALLRWNHPQLGAVSPARFLPVAEEQGMMPQLNDWVLRRACEQVADWRQRGVPVARVSVN
LSASSFESPRMLTDLLRLIDDMGVQPSDLTLEMTESVMLSGQPGVLENLHAIREAGISLS
LDDFGTGYSSLSHLHRLPIDELKLDMSFVRDIEHSEDARALTTSVLRIGEHLRKHVVAEG
VENEAQRLLLADLGCEVLQGYLFSRPLPAAALEAWLGAQS