Protein Info for Xcc-8004.2256.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: DNA mismatch repair protein MutL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 624 TIGR00585: DNA mismatch repair protein MutL" amino acids 1 to 307 (307 residues), 319.6 bits, see alignment E=1.5e-99 PF02518: HATPase_c" amino acids 21 to 77 (57 residues), 33.4 bits, see alignment 1.1e-11 PF13589: HATPase_c_3" amino acids 24 to 117 (94 residues), 37.3 bits, see alignment E=5.6e-13 PF01119: DNA_mis_repair" amino acids 211 to 326 (116 residues), 135.9 bits, see alignment E=1e-43 PF08676: MutL_C" amino acids 438 to 580 (143 residues), 163.8 bits, see alignment E=4.2e-52

Best Hits

Swiss-Prot: 100% identical to MUTL_XANCB: DNA mismatch repair protein MutL (mutL) from Xanthomonas campestris pv. campestris (strain B100)

KEGG orthology group: K03572, DNA mismatch repair protein MutL (inferred from 100% identity to xcb:XC_1817)

Predicted SEED Role

"DNA mismatch repair protein MutL" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4UVP3 at UniProt or InterPro

Protein Sequence (624 amino acids)

>Xcc-8004.2256.1 DNA mismatch repair protein MutL (Xanthomonas campestris pv. campestris strain 8004)
MAIRQLPEILINQIAAGEVVERPASVVKELVENALDAGATRVDIDLEEGGVRLIRIRDNG
GGIAPEELPLAVSRHATSKIASLDDLETVATLGFRGEALPSIASVSRFTLASRRPDAEHG
SALQIEGGRLGEVMPRAHAPGTTVEVRELFFNVPARRKFLRAERTELGHIEEWLRSLALA
RPDVELRVSHNGKPSRRYKPGDLYSDARLGETLGEDFARQALRVDHSGAGLRLHGWVAQP
HYSRASTDQQYLYVNGRSVRDRSVAHAVKMAYGDVLFHGRQPAYVLFLELDPARVDVNVH
PAKHEVRFREARLIHDFVYRTLQDALAQTRAGALPADVGVGGAAALGIGAVAAQGGGSYV
ADAGAGHPGAGSGSGYASWAPSQAPLGLRVDEARAAYAALYAPAAGSALRDDGQPVLSGT
GLPATAHDSGVPPLGYAVAQLHGIYILAENAEGLIVVDMHAAHERIGYERLKQAHDSIGL
HAQPLLVPMTLAVGEREADTAEREADTLASLGFEITRSGPQSLHVRSIPALLANADPEAL
LRDVLGDLREHGQSRRIATARDELLSTMACHGAVRANRRLTVPEMNALLRDMEATERSGQ
CNHGRPTWARFTLGEIDRWFLRGR