Protein Info for Xcc-8004.2165.1 in Xanthomonas campestris pv. campestris strain 8004
Annotation: Ornithine aminotransferase (EC 2.6.1.13); Succinylornithine transaminase (EC 2.6.1.81); Acetylornithine aminotransferase (EC 2.6.1.11); N-succinyl-L,L-diaminopimelate aminotransferase (EC 2.6.1.17)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to xca:xccb100_1791)Predicted SEED Role
"Ornithine aminotransferase (EC 2.6.1.13); Succinylornithine transaminase (EC 2.6.1.81); Acetylornithine aminotransferase (EC 2.6.1.11); N-succinyl-L,L-diaminopimelate aminotransferase (EC 2.6.1.17)" (EC 2.6.1.11, EC 2.6.1.13, EC 2.6.1.17, EC 2.6.1.81)
MetaCyc Pathways
- superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (16/18 steps found)
- aspartate superpathway (21/25 steps found)
- L-arginine biosynthesis III (via N-acetyl-L-citrulline) (9/9 steps found)
- L-lysine biosynthesis I (9/9 steps found)
- L-arginine biosynthesis I (via L-ornithine) (8/9 steps found)
- L-ornithine biosynthesis I (5/5 steps found)
- L-arginine degradation VI (arginase 2 pathway) (4/4 steps found)
- L-arginine degradation I (arginase pathway) (3/3 steps found)
- L-ornithine biosynthesis II (3/3 steps found)
- L-proline biosynthesis III (from L-ornithine) (3/3 steps found)
- L-arginine biosynthesis II (acetyl cycle) (8/10 steps found)
- L-citrulline biosynthesis (6/8 steps found)
- L-Nδ-acetylornithine biosynthesis (5/7 steps found)
- superpathway of arginine and polyamine biosynthesis (12/17 steps found)
- L-arginine degradation XIII (reductive Stickland reaction) (3/5 steps found)
- superpathway of L-citrulline metabolism (8/12 steps found)
- L-arginine degradation II (AST pathway) (1/5 steps found)
KEGG Metabolic Maps
- Arginine and proline metabolism
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Lysine biosynthesis
- Urea cycle and metabolism of amino groups
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.11, 2.6.1.17
Use Curated BLAST to search for 2.6.1.11 or 2.6.1.13 or 2.6.1.17 or 2.6.1.81
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0H2X856 at UniProt or InterPro
Protein Sequence (498 amino acids)
>Xcc-8004.2165.1 Ornithine aminotransferase (EC 2.6.1.13); Succinylornithine transaminase (EC 2.6.1.81); Acetylornithine aminotransferase (EC 2.6.1.11); N-succinyl-L,L-diaminopimelate aminotransferase (EC 2.6.1.17) (Xanthomonas campestris pv. campestris strain 8004) MSVLAPLAPLRAHAGRRLTAGLDDATIERLATDHPTLRQAIEAAGSEYALVQAEVADLLD LDEDAQISAVQDGFINFYADDAVTPYVALAARGPWVITLKGAVLYDAGGYGMLGFGHTPE AVLDAMARPQVMANVMTPSLAQRKLDRALRAEIGHTRGGCPFARFMCLNSGSEAVGLAAR IVDTNAKLHTDPGARHAGATIKRLVVKGSFHGRTDRPGLYSDSSRKTYSKYLASYRDEDS VIAIAPYDIAALQRAFDEAARNHWFIEAVFLEPVMGEGDPGRALPAEFYAAARTLTRNHG SLLLVDSIQAGLRAHGVLSVVDYPGFEQLDPPDLETYSKALNAAQYPLSVLAVTEQAAQV YRKGTYGNTMTTNPRALDVACATLALFTPQIRDNIRLRGAQALRKLEALQAELGGLITKV QGTGLLFSCELAPQYKCYGAGSTEEWLRHHGVNVIHGGENSLRFTPHFGMDEAELDLLVG LIAKALKEGPRQAQAEAA