Protein Info for Xcc-8004.2152.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Chaperone protein HtpG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 634 PF13589: HATPase_c_3" amino acids 32 to 148 (117 residues), 34.3 bits, see alignment E=3.4e-12 PF02518: HATPase_c" amino acids 32 to 185 (154 residues), 30.7 bits, see alignment E=5.4e-11 PF00183: HSP90" amino acids 227 to 629 (403 residues), 419 bits, see alignment E=5.2e-129

Best Hits

Swiss-Prot: 100% identical to HTPG_XANC8: Chaperone protein HtpG (htpG) from Xanthomonas campestris pv. campestris (strain 8004)

KEGG orthology group: K04079, molecular chaperone HtpG (inferred from 100% identity to xcb:XC_1721)

MetaCyc: 60% identical to chaperone protein HtpG (Escherichia coli K-12 substr. MG1655)
Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10, 5.6.1.7]

Predicted SEED Role

"Chaperone protein HtpG" in subsystem Protein chaperones

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.4.10 or 5.6.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4UVY7 at UniProt or InterPro

Protein Sequence (634 amino acids)

>Xcc-8004.2152.1 Chaperone protein HtpG (Xanthomonas campestris pv. campestris strain 8004)
MTVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPDLL
EGSGELRIRVDFDKDARTVTIDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDA
NLIGQFGVGFYSAFIVADQVDVYSRRAGLPASDGVHWSSRGEGEFEVASVDKPERGTRIV
LQLKEGEESFADGWTLRNILKKYSDHIGLPIEMRKEHYGEDADKPAEPEWEVVNRASALW
TRPKSEIKDEEYQEFYKHVAHDAGNPLAWSHNKVEGKLDYTSLLFVPGRAPFDLYHRDSA
KGLKLYVQRVFIMDQAEQFLPLYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKSALTK
RALDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANREKVAGLLRFSSTHDTTGAQSV
ALADYVGRMTEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTE
FDSKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGDDVAEVRVSHRLT
DSPAILAIGQGDLGLQMRQLLEASGQAVPETKPVFEFNPAHPLIEKLDAEQDMDRFGDLS
RVLFDQAALAAGDSLKDPAGYVRRLNKLLLELSA