Protein Info for Xcc-8004.2131.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Predicted 4-hydroxyproline dipeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 399 PF01321: Creatinase_N" amino acids 35 to 166 (132 residues), 71 bits, see alignment E=1.5e-23 PF00557: Peptidase_M24" amino acids 174 to 381 (208 residues), 190.4 bits, see alignment E=3.4e-60

Best Hits

KEGG orthology group: K01271, Xaa-Pro dipeptidase [EC: 3.4.13.9] (inferred from 100% identity to xca:xccb100_1756)

Predicted SEED Role

"Predicted 4-hydroxyproline dipeptidase" in subsystem Proline, 4-hydroxyproline uptake and utilization

Isozymes

Compare fitness of predicted isozymes for: 3.4.13.9

Use Curated BLAST to search for 3.4.13.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X6G6 at UniProt or InterPro

Protein Sequence (399 amino acids)

>Xcc-8004.2131.1 Predicted 4-hydroxyproline dipeptidase (Xanthomonas campestris pv. campestris strain 8004)
MSTQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLR
YFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVV
QAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACD
MTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQ
HLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVAC
EAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNE
PMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA