Protein Info for Xcc-8004.1489.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 770 PF13328: HD_4" amino acids 84 to 232 (149 residues), 70.7 bits, see alignment E=3.2e-23 TIGR00691: RelA/SpoT family protein" amino acids 106 to 767 (662 residues), 531.1 bits, see alignment E=2.1e-163 PF04607: RelA_SpoT" amino acids 291 to 401 (111 residues), 146.9 bits, see alignment E=6.7e-47 PF02824: TGS" amino acids 444 to 502 (59 residues), 74.2 bits, see alignment 1.7e-24 PF13291: ACT_4" amino acids 691 to 768 (78 residues), 68.5 bits, see alignment E=1.7e-22

Best Hits

KEGG orthology group: K00951, GTP pyrophosphokinase [EC: 2.7.6.5] (inferred from 100% identity to xca:xccb100_1217)

Predicted SEED Role

"GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I" in subsystem Stringent Response, (p)ppGpp metabolism (EC 2.7.6.5)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.6.5

Use Curated BLAST to search for 2.7.6.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X6R7 at UniProt or InterPro

Protein Sequence (770 amino acids)

>Xcc-8004.1489.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I (Xanthomonas campestris pv. campestris strain 8004)
LPIKALPGEPCVSAAGTHGREGARNTRCGDGDAHVTVAVSPHVPAAFVSTVVNSSAPDRL
HAVLQRPALASIAPALRDALAQAWAASETAQADSVPWALLTDTLDALAHLAADEATLVAA
LLFDIPALRPGVATLPWQPAERRGVVEGLLDGLDAADQVWALHAGREAGRNSEGLRRLLL
SIIHDLRVVPILLARQLARIRVADRQSEEERRALAQLTRDIHAPLANRLGIWQVKWELED
LAFRHLEPDTYRRIARDVDETRVARERYIEAVKRTLSAALAQQGLRADVSGRPKHIYSIW
RKMQKKRLSFDQLYDVRAVRVMVDDVAACYAALGAVHALWAPVPSEFDDYIARPKANDYR
SLHTAVVGPEGRTIEIQIRTHEMHAQAELGVAAHWKYKEGGKGAEKAFDRKILWMRQLLE
QVQDGEHGELAGALDAELIEDRVYALTPKGEVIDLPQGATPLDFAYHVHTMVGHRCRGAR
VNNRIVPLTYRLRSGDRVEIMTAKEADPRRDWLLASNGFLASGRSRDKVRAWFHKLDRAR
NVQAGKDVLDRELKRLGLQHADLSVATRKFHADSIDDLYIQVALGDTGPNQVSRALLEAE
RAASQPAVPAPPRPTARRDGLGKSKFTVQGVGNLLVQLARCCHPMAGEPIAGYLTRGRGI
TVHRADCVALSRLAAAHPQRVLPVEWGQAGSGYEVDVQVRAVDRRWLLKDITNLIAQEDA
HVLEINSDNVRDSGRAQLRLRLKVSDYEQLSALLGKLDALPGVNEVRRLG