Protein Info for Xcc-8004.139.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Ku domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR02772: Ku protein" amino acids 2 to 265 (264 residues), 332.9 bits, see alignment E=6.9e-104 PF02735: Ku" amino acids 11 to 194 (184 residues), 148.4 bits, see alignment E=1.2e-47

Best Hits

Swiss-Prot: 49% identical to KU_COXBR: Non-homologous end joining protein Ku (ku) from Coxiella burnetii (strain RSA 331 / Henzerling II)

KEGG orthology group: K10979, DNA end-binding protein Ku (inferred from 99% identity to xca:xccb100_0114)

Predicted SEED Role

"Ku domain protein" in subsystem DNA Repair Base Excision

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X2C3 at UniProt or InterPro

Protein Sequence (313 amino acids)

>Xcc-8004.139.1 Ku domain protein (Xanthomonas campestris pv. campestris strain 8004)
MARPIWTGTLSFGLLNVPVSLMSGERKVDLHFRMLDSRDKKPIRFERVNADTGDEVPWKE
IVKAFEYDKGSYVIVEEQDIRSAAPESHETVEVETFVDAADIDPRYFEKPYILVPGKKAE
KGYVLLRETMRDTGKVGIAKVVIRTREYLAAVMPQGDALILLLLRYQQEVVDPEDFKLPS
GAVSEYRITAKEQEMAKQLIESMSGRWQPEDYHDEFRGKLEQILRKRIQAKGGTTQVDDE
PAPHEDATTNVVDFMSLLQKSLQANTRTPAKKTTAAADTAPAKKTATKKAAKKATKKTAT
KATKKAAPRRKAG