Protein Info for Xcc-8004.1382.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: ClpB protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 861 TIGR03346: ATP-dependent chaperone protein ClpB" amino acids 6 to 858 (853 residues), 1464.6 bits, see alignment E=0 PF02861: Clp_N" amino acids 17 to 68 (52 residues), 47.1 bits, see alignment 1.1e-15 amino acids 95 to 145 (51 residues), 33.9 bits, see alignment 1.4e-11 PF00004: AAA" amino acids 203 to 336 (134 residues), 48 bits, see alignment E=9.1e-16 amino acids 602 to 720 (119 residues), 33.6 bits, see alignment E=2.5e-11 PF17871: AAA_lid_9" amino acids 342 to 444 (103 residues), 120.9 bits, see alignment E=1.1e-38 PF07724: AAA_2" amino acids 596 to 763 (168 residues), 235.4 bits, see alignment E=1.8e-73 PF00158: Sigma54_activat" amino acids 599 to 719 (121 residues), 23.6 bits, see alignment E=1.9e-08 PF07728: AAA_5" amino acids 601 to 728 (128 residues), 45.4 bits, see alignment E=4.1e-15 PF10431: ClpB_D2-small" amino acids 769 to 849 (81 residues), 96.5 bits, see alignment E=3.7e-31

Best Hits

Swiss-Prot: 72% identical to CLPB_PSEAE: Chaperone protein ClpB (clpB) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03695, ATP-dependent Clp protease ATP-binding subunit ClpB (inferred from 73% identity to aeh:Mlg_2558)

MetaCyc: 71% identical to protein disaggregase ClpB (Escherichia coli K-12 substr. MG1655)
RXN185E-10

Predicted SEED Role

"ClpB protein" in subsystem Protein chaperones or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H2X6N0 at UniProt or InterPro

Protein Sequence (861 amino acids)

>Xcc-8004.1382.1 ClpB protein (Xanthomonas campestris pv. campestris strain 8004)
MRMDKLTSRFQQALADAQSLAVGRDHNIIEPVHVLAALLDQSGGSTRPLLSQSGVNVPAL
RERLGEALDTLPKVSGQEGNLSIGNDLNRLLNQTDKLAQQHGDAFIASEWFVLAAADDAS
PLGVALRAAGGDKKKIEAAIDKLRGGETVQSENAEEQRQALEKYTIDLTARAESGKLDPV
IGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLRGKRVLSL
DMGALIAGAKFRGEFEERLKAVLSDLSKNEGQIILFIDELHTMVGAGKADGAMDAGNMLK
PALARGELHCIGATTLDEYRKYIEKDAALERRFQKVFVGEPTVEDTIAILRGLKERYAVH
HGVEITDPAIVAAATLSNRYITDRQLPDKAIDLMDEAASRIRMEIDSKPEELDRLERRLI
QLKIQREMLKKEKDEASRQRLADLESDIDKLEREFSDLNEVWKSEKAALQGTTKIKEQIE
HAKLELEAAQRRQDYAKMSEIQYGVLPQLEKQMLLANEVEHHDFKLVQDRVTAEEIAEVV
SRWTGIPVNKMLEGERDKLLRMEDELHRRVVGQEEAIKVVSDAVRRSRAGLSDPNRPSGS
FLFLGPTGVGKTELCKALADFLFDSTEAMIRIDMSEFMEKHSVSRLIGAPPGYVGYEEGG
YLTEAVRRRPYSLILLDEVEKAHADVFNILLQVLDDGRLTDGQGRTVDFRNTVIVMTSNL
GSHQIQELSGDGSAEAYTQMKAAVMGVVQAHFRPEFINRLDDIVVFHPLDKAQIKSIARI
QLQGLEKRLAERGLKLDLDDPALELLGNVGFDPVYGARPLKRAIQSQVENPLAQQILSGQ
YTSGDTVRVRTEGGHLAFTKG