Protein Info for Xcc-8004.1228.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: Xaa-Pro dipeptidase PepQ (EC 3.4.13.9)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 PF21216: PepQ_N" amino acids 9 to 155 (147 residues), 200 bits, see alignment E=2e-63 PF00557: Peptidase_M24" amino acids 167 to 427 (261 residues), 142.1 bits, see alignment E=2.1e-45

Best Hits

Swiss-Prot: 100% identical to PEPQ_XANC8: Xaa-Pro dipeptidase (pepQ) from Xanthomonas campestris pv. campestris (strain 8004)

KEGG orthology group: K01271, Xaa-Pro dipeptidase [EC: 3.4.13.9] (inferred from 100% identity to xcb:XC_0966)

MetaCyc: 47% identical to Organophosphorus acid anhydrolase-2 (Alteromonas sp.)
3.8.2.a [EC: 3.8.2.a]

Predicted SEED Role

"Xaa-Pro dipeptidase PepQ (EC 3.4.13.9)" (EC 3.4.13.9)

Isozymes

Compare fitness of predicted isozymes for: 3.4.13.9

Use Curated BLAST to search for 3.4.13.9 or 3.8.2.a

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4UY33 at UniProt or InterPro

Protein Sequence (441 amino acids)

>Xcc-8004.1228.1 Xaa-Pro dipeptidase PepQ (EC 3.4.13.9) (Xanthomonas campestris pv. campestris strain 8004)
MTQPSLSVLYSDHLRTLTARADQALQRGGFDHLVIPSGTTHYQLFDDRDYPFAVNPQFKA
WVPLTRMPHSWLVYTPGKRPTVIFYQPFDYWHVVPDAPSGWWVEHCDIHIIRTPEAALPL
LPARTERCAILGEAASALGACVPNNPAAVLDFLDYQRAFKTPYELAVMRLAQQLAVRGHR
AAEAAFRAGQSEFGIHMAYCSAVGQDANELPYGNIIALNEHGAVLHYTELGRQAPQPLRS
FLIDAGASAHGYASDITRTYAADAGSEFQALIDAVDAAQLRMGNAVRAGMDYKQLHVDAH
LSLMGILHDFGIITVSPEAALATGVSAAFFPHGLGHLIGLQVHDVAGFAASDRGGRIERP
DGHPYLRLTRVLEPGMVVTIEPGVYFIDMLLDEVKKNGHAASVNWDRVAQFAPYGGIRIE
DEVVCTDGDPENLTRPVFAAP