Protein Info for Xcc-8004.1066.1 in Xanthomonas campestris pv. campestris strain 8004

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 625 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 469 to 488 (20 residues), see Phobius details PF13667: ThiC-associated" amino acids 22 to 98 (77 residues), 102.2 bits, see alignment E=1.1e-33 TIGR00190: phosphomethylpyrimidine synthase" amino acids 138 to 590 (453 residues), 709.5 bits, see alignment E=6.4e-218 PF01964: ThiC_Rad_SAM" amino acids 139 to 586 (448 residues), 617.7 bits, see alignment E=9.8e-190

Best Hits

Swiss-Prot: 100% identical to THIC_XANCB: Phosphomethylpyrimidine synthase (thiC) from Xanthomonas campestris pv. campestris (strain B100)

KEGG orthology group: K03147, thiamine biosynthesis protein ThiC (inferred from 100% identity to xcc:XCC3319)

MetaCyc: 69% identical to phosphomethylpyrimidine synthase (Escherichia coli K-12 substr. MG1655)
PYRIMSYN1-RXN [EC: 4.1.99.17]

Predicted SEED Role

No annotation

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.99.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4UYF2 at UniProt or InterPro

Protein Sequence (625 amino acids)

>Xcc-8004.1066.1 hypothetical protein (Xanthomonas campestris pv. campestris strain 8004)
MNAAPTVLLQQTQTLSAAVTQPIPGSRKIFVQGSRADLQVPMREIVLTRTPTLFGGQDNP
PLSVYDTSGPYTDPQAAIDLAAGLAPLRADWIAERGDTLPLEALSSSFGRGREHDARLDA
VRFPSRRLPRVARSGANVTQMHYARRGIITPEMEFVAIRENQRLEAVTDAVLRKQHPGEA
FGAAIQQRITPEFVREEIARGRAILPNNINHPESEPMIIGRNFLTKINANIGNSAVSSGI
AEEVEKLVWSIRWGGDTVMDLSTGKHIHETRDWIIRNSPVPIGTVPIYQALEKVDGRAEE
LTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTARRVTGIVSRGGSILAKWCLAHHKE
NFLYTHFEDICEIMKAYDVAFSLGDGLRPGCIADANDAAQFGELETLGELTKLAWKHDVQ
TMIEGPGHVPMQLIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFG
TAMLCYVTPKEHLGLPNRQDVRDGIMAYKIAAHAADLAKGHPGVQVRDNALSKARFEFRW
DDQFHLGLDPEKAKEFHDETLPKDAHKLAHFCSMCGPHFCSMKITQDVRDYAAEHGISED
HALEAGMQEKSGEFVAQGAQVYRAS