Protein Info for TX73_024325 in Rhodopseudomonas palustris CGA009

Annotation: efflux RND transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1050 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 333 to 353 (21 residues), see Phobius details amino acids 360 to 377 (18 residues), see Phobius details amino acids 386 to 410 (25 residues), see Phobius details amino acids 431 to 451 (21 residues), see Phobius details amino acids 467 to 490 (24 residues), see Phobius details amino acids 517 to 539 (23 residues), see Phobius details amino acids 845 to 865 (21 residues), see Phobius details amino acids 872 to 892 (21 residues), see Phobius details amino acids 898 to 922 (25 residues), see Phobius details amino acids 946 to 967 (22 residues), see Phobius details amino acids 974 to 997 (24 residues), see Phobius details PF00873: ACR_tran" amino acids 6 to 1000 (995 residues), 773.6 bits, see alignment E=2.8e-236 PF03176: MMPL" amino acids 818 to 1006 (189 residues), 24.2 bits, see alignment E=1.6e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpa:RPA4680)

Predicted SEED Role

"RND multidrug efflux transporter; Acriflavin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1050 amino acids)

>TX73_024325 efflux RND transporter permease subunit (Rhodopseudomonas palustris CGA009)
MGLNVSSWSIRHPLPSIVFSIILLALGWISFTKLAVTRLPSADIPVISVAVSQFGAAPAE
LEAQVTKTIEDGVSGVEGVRHIASSITDGLSVTTIQFALETNTDRALNDVKDAVTRVRAN
LPQNINEPLIQRVDVIGLPIVTYAAISPGKTPEQLSWFVDDVVKRALQGVRGVAQVERIG
GVEREILVSLDPDRLKAAGLTALDVSRRLRGTNVDLAGGRAEIGNNDQAIRTLAGARTLN
DLAGTMISLNAGGEVRLDDLGTVTDTIAARHTFARFNGEPVVALGIKRSKGASDVVVAEA
VQKRIDTLKAQYPDVELKLIDTSVDYTKGNYEAAISTLFEGAILAVIVVFLFLRDFRATV
IAAISLPLSIFPAFWAMDMLGFSLNLVSFLAITLSTGILVDDAIVEIENIVRHMRMGKSP
YQAAIEAADEIGLAVIAISLTIIAIFAPASFMSGIAGQFFKQFGITVSVQVFFSLLAARF
VTPVLAAYFLKDHPHVEKPPGRVLRAYTRIVTWSVHHYYITVLIGLGIFAASIWSIVLLP
QGFLPAQDTARSVLAMQLPPGTQIGTTEKTTEAIVKLLRERPEVKSVFVDGGRVPPGIQE
VRRASLIINYTPKHDRSITQRELEHTISRQLDQVPDIRYWFLDENGLRAISLVVTGDDSA
VVNNVAQELASQMKRIPLVSNVISETALDRPELRIRPRADLAARLGVSTESLSETIRVAT
IGDVGPALAKFDAGDRLVPIRVQLEDSARGELATLEQLQVPIYGGRGAVPLSVVADVKFD
QGPTSINRYDRLRQATVAADLVGNSALGDATKQINELPVMKSLPKGVKVSPSGDAENLAE
LSDGFATAISGGLMMVYAVLVLLFGTFLQPITILFSLPLSIGGAIGALLLTGKQLTTPVW
IGILMLMGIVTKNAIMLIEFAMEAMREGKSRDAAIIDAGQKRARPIVMTTIAMVAGMTPS
ALAFGAGGEFRSPMALAVIGGLIFSTVLSLIFVPAVFMMMDDVGRGFWAVGKRLLSGSAR
AATEAATATATPSASAEPAPPAKKPSFWRG