Protein Info for TX73_024300 in Rhodopseudomonas palustris CGA009

Annotation: FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 535 PF07992: Pyr_redox_2" amino acids 10 to 61 (52 residues), 26.1 bits, see alignment 2e-09 PF01494: FAD_binding_3" amino acids 26 to 362 (337 residues), 196 bits, see alignment E=4e-61 PF01266: DAO" amino acids 27 to 63 (37 residues), 33.8 bits, see alignment 1e-11 PF13450: NAD_binding_8" amino acids 29 to 60 (32 residues), 23.6 bits, see alignment (E = 1.7e-08) PF21274: Rng_hyd_C" amino acids 426 to 535 (110 residues), 33.4 bits, see alignment E=1.7e-11

Best Hits

KEGG orthology group: K05712, 3-(3-hydroxy-phenyl)propionate hydroxylase [EC: 1.14.13.-] (inferred from 100% identity to rpa:RPA4675)

Predicted SEED Role

"Possible 3-(3-hydroxy-phenyl)propionate hydroxylase (EC 1.14.13.-)" in subsystem Homogentisate pathway of aromatic compound degradation (EC 1.14.13.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.14.13.-

Use Curated BLAST to search for 1.14.13.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (535 amino acids)

>TX73_024300 FAD-dependent oxidoreductase (Rhodopseudomonas palustris CGA009)
MAHQEHFQFGYRRHRDQDRQDPARHPVVVVGAGPVGLSLAIDLAQRGQNVVLLDDADRIG
EGSRAICFSKRALEVWDRLGVGAQMVEKGVVWQVGKIFRRDEMVYRFDLLPETGHKMPAF
INLQQYYAEAFLVGRVQQLPQIDLRWRNKVTALAQHNDHAELTIETPDGPYRLAADYVIA
CDGARSSLRGMVGAEFAGEVFEDQFLIADVKMTAAFPTERWFWFDPPFHSGQSALLHRQP
DDVWRIDLQIGPEADAAVERQPERVRPRIERMLGHGDFSFEWISIYKFQCRRMQRFLHER
VIFAGDSAHQVSPFGARGANSGLEDGENLAWKLDLVLRGQAPASLLDSYDIERSQAADDN
IRHSTRSTDFIAPHSKQERRLRDAVLALAHDVEFAKRMVNAGRLSTPSVYQSSLSTDDVD
VWSSGPVPGAAMRDAPLRAADGTLVYLTEAFMQAGGGFVLLERANGAAAPVPQGVRSLRI
GGDAPLRDDEGVFAARYDATPGAAYLLRPDGYVAARFRHPTQAAVDAALARACGR