Protein Info for TX73_023750 in Rhodopseudomonas palustris CGA009

Annotation: Do family serine endopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 520 transmembrane" amino acids 26 to 47 (22 residues), see Phobius details TIGR02037: peptidase Do" amino acids 71 to 507 (437 residues), 447.5 bits, see alignment E=2.6e-138 PF13365: Trypsin_2" amino acids 143 to 276 (134 residues), 117.6 bits, see alignment E=2.4e-37 PF00089: Trypsin" amino acids 144 to 298 (155 residues), 63.4 bits, see alignment E=8.5e-21 PF00595: PDZ" amino acids 307 to 393 (87 residues), 35.7 bits, see alignment E=2.9e-12 amino acids 426 to 488 (63 residues), 38 bits, see alignment E=5.5e-13 PF13180: PDZ_2" amino acids 316 to 406 (91 residues), 63.9 bits, see alignment E=4.3e-21 amino acids 428 to 497 (70 residues), 41.2 bits, see alignment E=5.2e-14 PF17820: PDZ_6" amino acids 342 to 393 (52 residues), 41.9 bits, see alignment 2.2e-14 amino acids 449 to 494 (46 residues), 43 bits, see alignment 9.7e-15

Best Hits

KEGG orthology group: K01362, [EC: 3.4.21.-] (inferred from 100% identity to rpa:RPA4572)

Predicted SEED Role

"Serine protease precursor MucD/AlgY associated with sigma factor RpoE" in subsystem Transcription initiation, bacterial sigma factors

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (520 amino acids)

>TX73_023750 Do family serine endopeptidase (Rhodopseudomonas palustris CGA009)
MEGDHFDHVSAQTEAHIRKVLRPRRLSLLASAAGLSMVVALGGAGFLTREMPSLTSSAYA
AENGKPAPAGFGDLVDKVKPAVISVRVKIDDDRQTTPLVRDDGDGDQMQMPRGLAPFQQF
ERQFGFRGPEGMPKRHQMITGEGSGFFITADGYAVTNNHVVDHAKSVQVTTDDGTIYTAK
VVGTDDKTDLALIKVDGKTDFPHVNFADSPARVGDWVIAVGNPFGLGGTVTAGIVSARGR
DIGSGPYDDYVQIDAPINKGNSGGPAFDTNGNVIGVNTAIYSPSGGSVGIGFDIPAATAK
LVVSQLKDKGYVTRGWLGVQVQPVTAEIADSLGMKQARGALVDGPQDGSPAAKAGIKAGD
VITAVDGKEVKDSRALARTISTLAPGSSVKLDVLHNGQSKTMDLTLAEMPGDHQKVADSS
GDRDATRPYLGLRVAPASEVDGAGKNGVVVTGVDPDGPAADKGLRTGDVILDVGGKSVTN
TGDVRNALTEASKDGKKTVLMRVKTADSAARFVAVPIAKG