Protein Info for TX73_022955 in Rhodopseudomonas palustris CGA009

Annotation: PepSY-associated TM helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 143 to 165 (23 residues), see Phobius details amino acids 193 to 217 (25 residues), see Phobius details amino acids 343 to 364 (22 residues), see Phobius details PF03929: PepSY_TM" amino acids 12 to 366 (355 residues), 195.7 bits, see alignment E=8e-62

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpa:RPA4429)

Predicted SEED Role

"Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (381 amino acids)

>TX73_022955 PepSY-associated TM helix domain-containing protein (Rhodopseudomonas palustris CGA009)
MRVPALKPILLQLHSVAGLVLAAVLVLVALTGAVMSFEDEIRGALDAGRVQLAPHAGSRM
PLDALIAKLQAGGDPVASITMPRSAASAAEVRFARKPDHTRPAPLYLDPYTGESLGHPAA
DAFFATVRKLHRWLLLPGDGNGYGRTITGVAALGLLAMLLTGLVLRWPHRPGSIKVWLKP
HWQLRGRGLHRSLHAVIGTWVLLLYLIMTLTGLWWSFDWYKTAATWLLARSPVTMQPPNR
AAVTAAPSAAISLDRVWATLVAERGDRFEAARLTLPSGREGTVRVRAWLTDARDGAHDEF
RIDGRSGQVLSADIYADKTIGEKVLARVLDIHRGSIFGWPGQLLFMLAAAAMPLFGVTGV
LLYLSRRRHQRMQRAARAKVG