Protein Info for TX73_022670 in Rhodopseudomonas palustris CGA009

Annotation: pitrilysin family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 signal peptide" amino acids 1 to 46 (46 residues), see Phobius details PF00675: Peptidase_M16" amino acids 76 to 205 (130 residues), 31.7 bits, see alignment E=1.4e-11 PF05193: Peptidase_M16_C" amino acids 212 to 387 (176 residues), 108.8 bits, see alignment E=3.1e-35

Best Hits

Swiss-Prot: 42% identical to Y4WB_SINFN: Uncharacterized zinc protease-like protein y4wB (NGR_a01030) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: None (inferred from 100% identity to rpa:RPA4373)

Predicted SEED Role

"ZINC PROTEASE (EC 3.4.99.-)" (EC 3.4.99.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.99.-

Use Curated BLAST to search for 3.4.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (477 amino acids)

>TX73_022670 pitrilysin family protein (Rhodopseudomonas palustris CGA009)
MSIDLLSARRVTAAVVVTRAGFAQRLALAACVGLAVALSAVPSHAAAKIQRLVTPGGLVA
WFVQDATVPLISMEYSFDGGASQDPADKPGVGHMVANLLDEGSGDMDSATFHERLDRRAI
QLSYSVTRDYFRGSLRMLKDDRNEAFGLLHTSMTQARFEPKDVERIRAQLLSTLRRQALD
PNNLASRKFLEVAFGDHPYGRPSTGTPESLPKVTTEDMKAYVGRVLAKDTLKIAVVGDVD
AATLAKLLDDTFGSLPAKAQLTPVPDVAAAKPPQRTNVTLDVPQTVVMFGGPGIKRDDPD
FMAAYVVNHILGGGSLSSRLYREVREKRGLAYSIYEQLLWMQHSALFIGSTGTRADRATE
TIDAITAEVKRIGEQGPSEQELSEAKSYINGSQMLSLDTSAKLAQALLQYQNDGLPIDYI
DKRSEVVNAVTLADAKRVAQRLWSNGLLTVVVGRQPQAAAQPAAVKPAGAPPAPRAN