Protein Info for TX73_022480 in Rhodopseudomonas palustris CGA009

Annotation: HAD family phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 PF00702: Hydrolase" amino acids 21 to 197 (177 residues), 105.4 bits, see alignment E=1.1e-33 PF13419: HAD_2" amino acids 24 to 203 (180 residues), 105.3 bits, see alignment E=8.4e-34 PF12710: HAD" amino acids 24 to 183 (160 residues), 31.9 bits, see alignment E=3.8e-11 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 95 to 203 (109 residues), 55.1 bits, see alignment E=1e-18 PF13242: Hydrolase_like" amino acids 158 to 204 (47 residues), 29.4 bits, see alignment 1.2e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpa:RPA4337)

Predicted SEED Role

"HAD-superfamily hydrolase subfamily IA, variant 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (247 amino acids)

>TX73_022480 HAD family phosphatase (Rhodopseudomonas palustris CGA009)
MSARGCEGEPQVVTGAHDWLIAAVLLDMDGTLVDTERLYLESLTEVLNAFGLPDAIETCE
SMVGLPGPECQALLVARYGETLPLREINRAFVEKRDARFAQGLPVKPGTCELLDALDDAG
CPVAVVTSSSRKTADMHLTLAGIRARFATILTRDDVVHGKPAPDLYLLAANRLGVPPAHC
VAVEDSSVGVASAFTAGAITLMVPDLLQPDDATRGKCAAVLPDLNAVRSLLEIRGRFAAP
DAALAPR