Protein Info for TX73_022065 in Rhodopseudomonas palustris CGA009

Annotation: NADH-quinone oxidoreductase subunit NuoG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 877 PF13510: Fer2_4" amino acids 5 to 79 (75 residues), 53.3 bits, see alignment E=5.8e-18 TIGR01973: NADH dehydrogenase (quinone), G subunit" amino acids 6 to 638 (633 residues), 549.1 bits, see alignment E=8.1e-169 PF00111: Fer2" amino acids 9 to 73 (65 residues), 35.8 bits, see alignment 1.5e-12 PF10588: NADH-G_4Fe-4S_3" amino acids 90 to 127 (38 residues), 51.8 bits, see alignment (E = 1.2e-17) PF04879: Molybdop_Fe4S4" amino acids 223 to 275 (53 residues), 50.9 bits, see alignment 3.2e-17 PF00384: Molybdopterin" amino acids 495 to 633 (139 residues), 35.1 bits, see alignment E=2e-12

Best Hits

KEGG orthology group: K00336, NADH dehydrogenase I subunit G [EC: 1.6.5.3] (inferred from 100% identity to rpa:RPA4259)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (877 amino acids)

>TX73_022065 NADH-quinone oxidoreductase subunit NuoG (Rhodopseudomonas palustris CGA009)
MTKKKIEIDGRVIEAKDGEDLLSACLTHGIDVPYFCWHGALGSVGACRQCAVKVYDGPDD
TEGRIVMSCMTPVADVERVSVTDPEAVAFRAQVIEWLMVNHPHDCPVCEEAGSCHLQDMT
IATGHIDRRYKFTKRTHRNQDLGPLVTHEMNRCIACYRCTRFYRDYAGGRDLDAFGAHDN
VYFGRAEDGPLESPFAGNLAEVCPTGVFNDKGWSRDYSRKWDMRATPSICPHCSVGCNIL
VDQRDGRVKRVQNRYHGALNGYFICDRGRYGPLHVVSEHRLRQPLIGGVPASEHEAASAA
HAIVAEGAIGIGSPRASLEANYALQRLVGPERFFAGVSDVEAGLVRRIVEILRAGPAKIA
SLHEVEHADAALVLGENLTGTAPRLALALRQTARGAERELAAQKGVHAFLDPAVRTAGEG
RRSPIVLATPLPDALDDLAALSLRLDPQGIAAFGDSVAAALGAGPADAIEEHSEAARVAE
ILANAERPLIVAGCALMSPEIIEAAARIVAALGVKARIVLLAPEANSIGLALLGGDGLDS
AAALLERGGAKTAIVLENDLFDRAPRAGVERLFAAAKGVVALDSMANETTARAAVALPVA
PFTEATGTFVNYEGRAQRFFAAVAPQEAAPASWRRLDAFGAGDWHGLDALIGDLIVERPD
LVAVADAAPGEDFGMADGKVTRAPRPYTGRTADDRAGQFADAVIPVDQDGPLTFGIKGAR
GTAVPAPLITSYKTSGQHSANNVTRFLEEVGGPLRGGDPGALLIKSGEASLPDAVLQPVH
AGEGLWLIPLHDAFTGGELSRASALLAARRPAPRLLLHPDDAALHGFRDGAAVRVDGNPC
APVVTLDASVPRGTVVISAGSCQPRGPLRRVKVEAAP