Protein Info for TX73_022040 in Rhodopseudomonas palustris CGA009

Annotation: proton-conducting transporter membrane subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 689 signal peptide" amino acids 5 to 6 (2 residues), see Phobius details transmembrane" amino acids 7 to 23 (17 residues), see Phobius details amino acids 30 to 51 (22 residues), see Phobius details amino acids 57 to 79 (23 residues), see Phobius details amino acids 86 to 107 (22 residues), see Phobius details amino acids 119 to 137 (19 residues), see Phobius details amino acids 143 to 161 (19 residues), see Phobius details amino acids 174 to 195 (22 residues), see Phobius details amino acids 213 to 231 (19 residues), see Phobius details amino acids 251 to 273 (23 residues), see Phobius details amino acids 279 to 300 (22 residues), see Phobius details amino acids 308 to 337 (30 residues), see Phobius details amino acids 343 to 362 (20 residues), see Phobius details amino acids 374 to 397 (24 residues), see Phobius details amino acids 416 to 438 (23 residues), see Phobius details amino acids 451 to 477 (27 residues), see Phobius details amino acids 489 to 510 (22 residues), see Phobius details amino acids 617 to 635 (19 residues), see Phobius details amino acids 641 to 657 (17 residues), see Phobius details amino acids 669 to 687 (19 residues), see Phobius details PF00662: Proton_antipo_N" amino acids 70 to 120 (51 residues), 31.7 bits, see alignment 1.1e-11 PF00361: Proton_antipo_M" amino acids 136 to 425 (290 residues), 232.7 bits, see alignment E=5.5e-73

Best Hits

KEGG orthology group: K00341, NADH dehydrogenase I subunit L [EC: 1.6.5.3] (inferred from 100% identity to rpa:RPA4254)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (689 amino acids)

>TX73_022040 proton-conducting transporter membrane subunit (Rhodopseudomonas palustris CGA009)
MAHLLPFVPVPALLGFVFLSLIPAPLSRAAVIALGVGAAVLPAILFFPVALSCIEGVCVA
GATVPILSIDTGVFVAQIAMSMDPLSMVTGGTVVLVGALVLIYSGAYMASEPLQDLRRFF
AVMNLFLAGMLAVVFAADVILLFLGWETIGLCSFMLIAFYDRLPKAVAAGRKALITTRVA
DSLLLAGLMMLFLNAGTTRLDGMLAAVPSIDPWRLAPIAGLIALGALGKSAQIPFHTWLP
SAMAGPTPVSALLHSATMVAAGVILLARLAPLFAAAPEISAMVAMLGILTAALGALVALI
QTDVKKLLAFSTMSQIGFMVLALGLGAPAVALSHFAIHAAFKSLLFLSAGVMSHAAGGST
AIEALRGSRYRQPLAFWSFAIGAASLAGLPVITAGWYSKEAVLAAVWSSGPWGVPLWLLA
ATAAVLTGAYAFRVVFVAASQTADLAAPPWGGLAVVVPLSVLTFVAVVGGMSVGALISFT
GGAPEHIPLVPALLGAAAPILGVVLARWLVRHPQELERLATRMRHIRIFRVDVLYYYYFV
RRFRRVATVLGNAEGTEAVADAVALRREGVDVPGLVTDDPLGRGASQVRGIRTDLITRAT
DGQTPVVRMVAGDPVGRLLIVVARLFVGFFVARFNPDRIDRAWMGLASGAGHAWALVRLT
QTGRVRDHSLWIALGCAGLLLFAWGTSWR