Protein Info for TX73_020735 in Rhodopseudomonas palustris CGA009

Annotation: acyl-CoA dehydrogenase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 PF02771: Acyl-CoA_dh_N" amino acids 30 to 153 (124 residues), 47.2 bits, see alignment E=5.5e-16 PF02770: Acyl-CoA_dh_M" amino acids 157 to 257 (101 residues), 59.7 bits, see alignment E=5.2e-20 PF00441: Acyl-CoA_dh_1" amino acids 270 to 419 (150 residues), 113.3 bits, see alignment E=2.4e-36 PF08028: Acyl-CoA_dh_2" amino acids 287 to 401 (115 residues), 37.5 bits, see alignment E=5.3e-13

Best Hits

KEGG orthology group: K00249, acyl-CoA dehydrogenase [EC: 1.3.99.3] (inferred from 100% identity to rpt:Rpal_4526)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7, 1.3.99.3

Use Curated BLAST to search for 1.3.8.7 or 1.3.99.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (423 amino acids)

>TX73_020735 acyl-CoA dehydrogenase family protein (Rhodopseudomonas palustris CGA009)
MQTAYVPRQTPYTLAPEDALNDLRMSEAVRPLYDHVKKFIADVVEPMQHEFEIAEAKNPN
RWSFSQEQLDLLAKAKAQAKEQGLWNFFLPDAETGEGLNNLDYAYIAAELGKAPLASEVM
NCSAPDTGNMEVLERVGTPEQKEKWLKPLLDGEIRSAYVMTEPNVASSDAKNVSTSAVLD
GNEWVINGEKYYISGLGDPRCKIMIVMVKTDPTAAPSKQQSQILVPVDTPGVEVLGPMHV
FGHDHAPRGHMHMRFNNVRVPKENILLGEGRGFEISQLRLGPGRIHHCMRTIGKAEKALD
LMVARGLTREAFGKKLAHLGGNLQIIAQARCEIEAMRLMVLKAAKAMDVLGNKEARVWVS
MVKAMVPERACKIIDQAIQMHGATGISQWTPLAEMYTDVRHLRFADGPDEVHWMVVGRHE
LTL