Protein Info for TX73_020730 in Rhodopseudomonas palustris CGA009

Annotation: DEAD/DEAH box helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 691 PF00270: DEAD" amino acids 23 to 191 (169 residues), 148.5 bits, see alignment E=3.2e-47 PF04851: ResIII" amino acids 34 to 189 (156 residues), 23.8 bits, see alignment E=7.7e-09 PF00271: Helicase_C" amino acids 235 to 338 (104 residues), 87.3 bits, see alignment E=1.8e-28 PF03880: DbpA" amino acids 483 to 548 (66 residues), 48 bits, see alignment E=2.1e-16

Best Hits

KEGG orthology group: K05592, ATP-dependent RNA helicase DeaD [EC: 3.6.4.13] (inferred from 100% identity to rpa:RPA4001)

Predicted SEED Role

"ATP-dependent RNA helicase"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (691 amino acids)

>TX73_020730 DEAD/DEAH box helicase (Rhodopseudomonas palustris CGA009)
MTFPTSPPPLARALAERNYLQATPVQSAVLAPDTAGRDLLVSAQTGSGKTVAYGLAIAQD
LLGDAEQFAPAAAPLALIVAPTRELALQVHRELSWLYRHAGGRIVSCVGGMDPRREQREL
ADGAHIVVGTPGRLCDHLRRNRLDVSQLKAVVLDEADEMLDLGFREDMEFILETTPETRR
TLLFSATLPRGIIALAKTYQHDAMRIEVEGAEGGHADIEYRAIRIAPNDVEHAVVNVLRY
VESPTAIVFCNTRSAVNHLQTALLERGFAVVALSGELTQNERTGALNALRDGRARVCVAT
DVAARGIDLPNLGLVIHAELPNDAEVMQHRSGRTGRAGNKGVSVLLVPPARRRRAELLLQ
LAGIEANWGTAPQADEIRSLDQQRMLQDPLFTEEPTAEDQALAQALLAERSPEQIAVALA
RVVRARMPAPEDILDPGERPARGRDERPGKTAREPRDHEARDKAPRSRSAKAGEKHAITG
GVWFRAAIGKRKNAEARWLLPMICRRGGITRQDIGAIRILDTTTEFEISSAAADAFAAQI
KRPDHDDNIRIEPLIGAKPIPPRDDNRPPRQDADRKPDRETRRAKRPDSWSPLSGEPLPD
PREQDAPRPGKRVPHDDAPRGGKPARFKDKGFKTRGEDAFEGDFKAKPFKTDGFKAGKAK
GDKPAYVSKARRADPSAKNPPFKKKAKKKFR