Protein Info for TX73_020130 in Rhodopseudomonas palustris CGA009

Annotation: ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 854 transmembrane" amino acids 25 to 46 (22 residues), see Phobius details amino acids 55 to 80 (26 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 89 to 208 (120 residues), 34.8 bits, see alignment E=7.7e-13 PF00989: PAS" amino acids 90 to 200 (111 residues), 24.6 bits, see alignment E=7.6e-09 PF08448: PAS_4" amino acids 99 to 204 (106 residues), 32.1 bits, see alignment E=4.1e-11 amino acids 347 to 457 (111 residues), 41.2 bits, see alignment E=6.2e-14 PF00512: HisKA" amino acids 472 to 534 (63 residues), 30.1 bits, see alignment 1.5e-10 PF02518: HATPase_c" amino acids 578 to 698 (121 residues), 82.8 bits, see alignment E=8.3e-27 PF00072: Response_reg" amino acids 736 to 848 (113 residues), 78.6 bits, see alignment E=1.4e-25

Best Hits

KEGG orthology group: K13587, two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC: 2.7.13.3] (inferred from 100% identity to rpa:RPA3882)

Predicted SEED Role

"multi-sensor hybrid histidine kinase"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (854 amino acids)

>TX73_020130 ATP-binding protein (Rhodopseudomonas palustris CGA009)
MTINDQQASPEPRPASPEPARRGGSIALVLLLAGAIVAAAVAFMTLGRAGAQPYILGLLA
LLAMVGLFMLFAFAAGIIGFADRAAEDPILRAIPENAFDGIAVTDAGGHVVYANSTYLAL
TGAATMQDVRPVERVFIGNPDVSEAVFRLLKAAREGRRLQEEVRVAGADGTQGRWMRLRV
RPLGTSKREARQTVWSIADITRDRERQEDVFQTLQHAIEYLDHAPCGFFSVNPAGNLVYV
NATLANWLDHDLAEIGSGGLKLSDVVSGDGAALLTSIVPEPGEVKTEVFDIDLKKRGGQT
VPVRLYHKLAFGADGTPGPSRTLVISRARDDRLDPQRAAEIRFMRFFDQTPMAIATVDKT
GAVVRANARLAKLAQSLDPAGAVASKSILAAASARDRAVLAGAIEQAAKGQADIAPVEVM
LASAKERWGQFFVTAVSDETDNEAAIVHMLETTERRALENQVNQAQKMDTIGQLAGGIAH
DFNNVLSAIMMANDFLLNAHKPTDPSFQDIMQIKQNATRAATLVRQLLAFSRKQTLRPQV
LDLGEALTDIDRLLKRLIGEKISLEMQHGRDLWRTKADVSQFEQVIVNLAVNARDAMPDG
GKLTIRTANVTASEASQLGHNGMPAADYVCVEVSDTGTGIPPEIVDKIFEPFFSTKEVGK
GTGLGLSTVYGIIKQTGGFVYVDSEIGKGTTFRIYLPRHDAATEPQPEAPAVSAAAPEPA
PTAPKPRADMTGQGTILLVEDEEGLRSLNARGLRSRGYEVIEASNGVEALEEFDAHGGEV
DLVVSDVVMPEMDGPTLLKAMRGRNPDLKIIFVSGYAEDAFEKSLPENEQFAFLAKPFAL
SALVAKVKETMGAS