Protein Info for TX73_019220 in Rhodopseudomonas palustris CGA009

Annotation: NirA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 590 TIGR02435: precorrin-3B synthase" amino acids 84 to 505 (422 residues), 525.7 bits, see alignment E=3.6e-162 PF03460: NIR_SIR_ferr" amino acids 110 to 168 (59 residues), 54.8 bits, see alignment 6.3e-19 amino acids 361 to 427 (67 residues), 65.8 bits, see alignment E=2.4e-22 PF01077: NIR_SIR" amino acids 179 to 337 (159 residues), 102.9 bits, see alignment E=1.2e-33 amino acids 442 to 555 (114 residues), 49.9 bits, see alignment E=2.6e-17

Best Hits

KEGG orthology group: K00366, ferredoxin-nitrite reductase [EC: 1.7.7.1] (inferred from 100% identity to rpa:RPA3710)

Predicted SEED Role

"Ferredoxin--nitrite reductase (EC 1.7.7.1)" in subsystem Nitrate and nitrite ammonification (EC 1.7.7.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.7.7.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (590 amino acids)

>TX73_019220 NirA family protein (Rhodopseudomonas palustris CGA009)
MGSEFSIDQKRYLEGFATGVTAARAARGSLPAGSAASPSGPDAIHHQAQDRVTASGKKLN
DQEKWKREQHPFDAYARLKQQAKDNAAPKPADNFRWRYYGLFYVAPAQTSYMCRLRIPNG
ILTSWQMAGLAYLADTLADGYAHVTTRANLQMREIAPKDAVQLLQGIESLGLWARGSGAD
NIRNVTGSATAGIDPQELIDTRAYARDWHFYILNERALFGLPRKFNVAFDGGGLIPTLED
TNDIAFQAVTIGDGHGVAPGVYFRLALGGITGHKDFARDTGVIVAPDEATEVADAIVRVF
IEHGDRTDRNKARLKYVLDAFGFDKYLELVEDKLGRKLIRVPAEAAAPRPAQDRAAHLGV
HPQQQAGMNWIGVRLATGHLTSVQMRGLAEIARSFGDGDLRLTVWQNLLISGVPDARVTD
ATAAIEALGLAITASPLRAGLIACTGASGCRFAAAHTKETAEAIAQYCEPRVPLDTPINI
HLTGCHNSCAQHFISDIGLIGAKVAVSDEDSVEGFHIHVGGGFGVDAAIGTEVLRDVKQD
DAPRVIERMLQTYLARRASPAETFLAFVRRQDAAALQQLFAYEQSPETVA