Protein Info for TX73_019145 in Rhodopseudomonas palustris CGA009
Annotation: prephenate dehydratase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K04518, prephenate dehydratase [EC: 4.2.1.51] (inferred from 100% identity to rpt:Rpal_4217)Predicted SEED Role
"Prephenate dehydratase (EC 4.2.1.51)" in subsystem Chorismate Synthesis or Phenylalanine and Tyrosine Branches from Chorismate (EC 4.2.1.51)
MetaCyc Pathways
- superpathway of aromatic amino acid biosynthesis (18/18 steps found)
- superpathway of L-phenylalanine biosynthesis (10/10 steps found)
- L-phenylalanine biosynthesis I (3/3 steps found)
- L-phenylalanine biosynthesis III (cytosolic, plants) (2/2 steps found)
- superpathway of chorismate metabolism (40/59 steps found)
KEGG Metabolic Maps
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of phenylpropanoids
- Phenylalanine, tyrosine and tryptophan biosynthesis
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.2.1.51
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (280 amino acids)
>TX73_019145 prephenate dehydratase (Rhodopseudomonas palustris CGA009) MKIAFQGEPGANSHIAISDAYPTAEAMPCATFEDALSAISSGEADLGMIPIENSVAGRVA DIHHLLPTSKLFIVGEWFLPIRHQLVAVPGAKLEDIKTVESHVHALGQCRRIIRKFGLKP IVAGDTAGSARIIAERGDKTCAAISSRLAAKIYGLDILAEDIEDEAHNTTRFVVLAREPR WAVQGSGKLVTTFVFRVRNLPAALYKALGGFATNGVNMTKLESYMVDGNFFATQFYADVE GHPEDRNLAFALDELKFFSREFRIVGVYPGHPFRATFSER