Protein Info for TX73_018855 in Rhodopseudomonas palustris CGA009

Annotation: gluconokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 182 TIGR01313: carbohydrate kinase, thermoresistant glucokinase family" amino acids 17 to 172 (156 residues), 179.9 bits, see alignment E=1.7e-57 PF13238: AAA_18" amino acids 18 to 132 (115 residues), 30.1 bits, see alignment E=9.6e-11 PF13671: AAA_33" amino acids 18 to 150 (133 residues), 33 bits, see alignment E=1e-11 PF01202: SKI" amino acids 24 to 132 (109 residues), 34 bits, see alignment E=4.8e-12

Best Hits

Swiss-Prot: 43% identical to GNTK_SCHPO: Probable gluconokinase (SPAC4G9.12) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K00851, gluconokinase [EC: 2.7.1.12] (inferred from 100% identity to rpa:RPA3638)

Predicted SEED Role

"Gluconokinase (EC 2.7.1.12)" in subsystem D-gluconate and ketogluconates metabolism or Entner-Doudoroff Pathway (EC 2.7.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (182 amino acids)

>TX73_018855 gluconokinase (Rhodopseudomonas palustris CGA009)
MPVSPEPMTSEPRPRALIVMGVSGSGKSTVGEALAQRLGWRYEDADAYHPKANVAKMSAG
QPLTDDDRWPWLKAIAAEIDRVIAGGGHIVFGCSALKGAYRDVLVHGRDDIRIVFLDGSR
ELIGGRMAARKNHFMPAGLLDSQFATLERPGPDERPIIASIDAPVATIVDDIVGQLPTST
SD