Protein Info for TX73_018705 in Rhodopseudomonas palustris CGA009

Annotation: energy-dependent translational throttle protein EttA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 549 TIGR03719: ATP-binding cassette protein, ChvD family" amino acids 4 to 547 (544 residues), 958.1 bits, see alignment E=1.4e-292 PF00005: ABC_tran" amino acids 22 to 185 (164 residues), 93.6 bits, see alignment E=3.6e-30 amino acids 334 to 467 (134 residues), 91.5 bits, see alignment E=1.6e-29 PF12848: ABC_tran_Xtn" amino acids 224 to 294 (71 residues), 47.2 bits, see alignment E=3.9e-16

Best Hits

Swiss-Prot: 61% identical to ETTA_MYCTU: Energy-dependent translational throttle protein EttA (ettA) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 100% identity to rpt:Rpal_4129)

Predicted SEED Role

"ABC transporter, ATP-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (549 amino acids)

>TX73_018705 energy-dependent translational throttle protein EttA (Rhodopseudomonas palustris CGA009)
MARQFVYFMQGLTKAYPTRKVLDNVHLSFYPDAKIGVLGVNGAGKSTLLKIMAGIDKEYT
GEAWVAEGARVGYLEQEPQLDPALTVRENVMLGVAKQKAILDRYNELAMNYSEETADEMT
ALQDQIESAGLWDLDSKVDQAMDALRCPPDDADVTKLSGGERRRVALCKLLLDQPDLLLL
DEPTNHLDAESVSWLESHLRNYPGAILIVTHDRYFLDNVTSWILELDRGRGIPYEGNYSS
WLVQKQKRLLQEGREDAAHQKTLEREQEWIASSPKARQAKSKARYQRYEELLAKASEKQT
QTAQIIIPVAERLGNNVVDFEHLTKGFGDKLLIDDLTFKLPPGGIVGVIGPNGAGKTTLF
RMITGQEKPDQGTITVGETVHLGYVDQSRDSLDAKKTVWEEISGGNELILLGKKEVNSRG
YCSAFNFKGGDQQKKVGSLSGGERNRVHLAKMLKSGANVLLLDEPTNDLDVDTLRALEEA
LEDFAGCAVIISHDRWFLDRIATHILAFEDDSHVEWFEGNFQDYEKDKMRRLGQDAIIPH
RAKYKKLTR