Protein Info for TX73_018415 in Rhodopseudomonas palustris CGA009

Annotation: ACR3 family arsenite efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 transmembrane" amino acids 7 to 27 (21 residues), see Phobius details amino acids 44 to 64 (21 residues), see Phobius details amino acids 78 to 102 (25 residues), see Phobius details amino acids 114 to 134 (21 residues), see Phobius details amino acids 153 to 173 (21 residues), see Phobius details amino acids 179 to 201 (23 residues), see Phobius details amino acids 213 to 234 (22 residues), see Phobius details amino acids 245 to 268 (24 residues), see Phobius details amino acids 280 to 302 (23 residues), see Phobius details amino acids 308 to 330 (23 residues), see Phobius details TIGR00832: arsenical-resistance protein" amino acids 1 to 329 (329 residues), 376.3 bits, see alignment E=7e-117 PF13593: SBF_like" amino acids 11 to 311 (301 residues), 27.5 bits, see alignment E=1.9e-10 PF01758: SBF" amino acids 48 to 242 (195 residues), 108.9 bits, see alignment E=2.6e-35

Best Hits

KEGG orthology group: K03325, arsenite transporter, ACR3 family (inferred from 100% identity to rpa:RPA3553)

Predicted SEED Role

"Arsenical-resistance protein ACR3" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (350 amino acids)

>TX73_018415 ACR3 family arsenite efflux transporter (Rhodopseudomonas palustris CGA009)
MSTFERYLTLWVALCIVVGIGLGHLMPGAFQVIGAAEIAKVNLPVAALIWLMIIPMLVRI
DFAALGRVREHWRGIGVTLFINWAVKPFSMAALAWLFVGYLFRPYLPADQINSYIAGLII
LAAAPCTAMVFVWSNLTKGEPHFTLSQVALNDTIMVFAFAPIVGLLLGLSAITVPWDTLV
LSVVLYIVVPVIIAQGLRRWALASGGEAQLQRLLGIFQPLSLVALLATLVLLFGFQGEQI
IRQPLVIALLAVPILIQVYFNAGLAYLLNRLSGEQHCVAGPSALIGASNFFELAVAAAIS
LFGFESGAALATVVGVLIEVPVMLTVVAIVNRSKRWYEADQRAPVARTPG