Protein Info for TX73_017265 in Rhodopseudomonas palustris CGA009

Annotation: non-ribosomal peptide synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 637 PF00501: AMP-binding" amino acids 26 to 369 (344 residues), 264.2 bits, see alignment E=2.6e-82 TIGR01733: amino acid adenylation domain" amino acids 46 to 444 (399 residues), 368.7 bits, see alignment E=1.8e-114 PF13193: AMP-binding_C" amino acids 429 to 505 (77 residues), 38.1 bits, see alignment E=3.6e-13 PF00550: PP-binding" amino acids 539 to 596 (58 residues), 42.8 bits, see alignment 7.6e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpa:RPA3340)

Predicted SEED Role

"Non-ribosomal peptide synthetase modules and related proteins"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (637 amino acids)

>TX73_017265 non-ribosomal peptide synthetase (Rhodopseudomonas palustris CGA009)
MASTVVIKEGSGSGAVAACTVPQVLEQIAQSFPESIAAISERGRITFAELEFRSNQLARL
LVKRGVKVGAIVVLMTGRSIDTLIGMTAILKAGGVYMPLDVGLGPEAISGAIQDAQPALV
LTEHQPALIDAIEQRRLSDELDASRLEPGDPLALELTPSLPAYVMFTSGSTGRPKGVVVP
HRAIVRLVVDTDFMTLSPATVMLHAAPLAFDASTLEIWGPLLNGGQIVIVEDAVLSVDRI
AETLGRFSVNAAWLTAGLFHLMVDERPEALSGLTTLLAGGDVLSPAHVRRAMALLPDCTI
VNGYGPTENTTFTCCYSIPRTGWGDGPVPIGFPISGTSVHILSDTLEPVADGEEGQLCAG
GIGLALGYLNRPELTAEKFIVDPLSDDPAARLYLTGDYVRRRSDGAIEFRGRRDRQVKIN
GVRIELDGVEQALRQDPVLADAAVVLSADRGDAKRIVAFLKPLPGDAAGDLEAGVIRRLK
EQFPAQAIPSTIKVVDELPLNKNGKIDRAKLLSDLIATEQLGAGTDEEDFSDDSVGSIVA
DIWSALLGKSVDARANLFDLGATSLQMIAAHERIQAAIGIRFPVTDLFAHPSIAEFQACL
DGASHRSLAIAGAARGRRQRRAMNAAYGAINVRSHHA