Protein Info for TX73_016660 in Rhodopseudomonas palustris CGA009

Annotation: DegQ family serine endoprotease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details TIGR02037: peptidase Do" amino acids 37 to 460 (424 residues), 475 bits, see alignment E=1.2e-146 PF00089: Trypsin" amino acids 85 to 247 (163 residues), 70.2 bits, see alignment E=6.1e-23 PF13365: Trypsin_2" amino acids 88 to 224 (137 residues), 117.9 bits, see alignment E=1.6e-37 PF13180: PDZ_2" amino acids 266 to 355 (90 residues), 44.7 bits, see alignment E=3.5e-15 amino acids 396 to 439 (44 residues), 27.5 bits, see alignment 8.1e-10 PF17820: PDZ_6" amino acids 291 to 344 (54 residues), 33.5 bits, see alignment 7.5e-12

Best Hits

KEGG orthology group: K01362, [EC: 3.4.21.-] (inferred from 100% identity to rpt:Rpal_3637)

Predicted SEED Role

"Serine protease precursor MucD/AlgY associated with sigma factor RpoE" in subsystem Transcription initiation, bacterial sigma factors

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (463 amino acids)

>TX73_016660 DegQ family serine endoprotease (Rhodopseudomonas palustris CGA009)
MNPIRTFAVLCVSLALTTPLAAQDRRVPSSPAELKLSYAPIVQHVQPAVVNVYAAKVVQN
RNPLLEDPIFRRFFGVPGQPEQIQRSLGSGVMVDASGLVVTNNHVIEGADQVKVALADKR
EFEAEIVLKDSRTDLAVLRLKDTSEKFPTLDFANSDDLLVGDVVLAIGNPFGVGQTVTHG
IVSALARTQVGITDYQFFIQTDAAINPGNSGGALVDVSGKLVGINTAIFSRSGGSQGIGF
AIPANMVRVVVASAKSGGKAVKRPWLGARLQAVSPEIAETLGLKRPGGALVASVTKGSPA
ERAGLKLSDLIVSIDGFAIDDPNAFDYRFATRPLGGAAQLEVQRSGKAVKLSIPLETAPD
SGRDELVITSRSPFQGAKIANISPAIADEMRLDPSVEGVVVTDLPDDSTAANVGFQKGDI
IVAVNNTRIGKTSDLERVAGQTARLWRIMLVRGGQQIQVTLGG