Protein Info for TX73_015255 in Rhodopseudomonas palustris CGA009

Annotation: NADH-quinone oxidoreductase subunit NuoG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 691 PF13510: Fer2_4" amino acids 1 to 68 (68 residues), 51.7 bits, see alignment E=1.8e-17 TIGR01973: NADH dehydrogenase (quinone), G subunit" amino acids 4 to 599 (596 residues), 720.8 bits, see alignment E=8.3e-221 PF00111: Fer2" amino acids 6 to 54 (49 residues), 32.8 bits, see alignment 1.3e-11 PF10588: NADH-G_4Fe-4S_3" amino acids 91 to 130 (40 residues), 65.8 bits, see alignment 5e-22 PF00384: Molybdopterin" amino acids 279 to 601 (323 residues), 342.6 bits, see alignment E=6.8e-106 PF09326: NADH_dhqG_C" amino acids 633 to 678 (46 residues), 63.5 bits, see alignment 6e-21

Best Hits

Swiss-Prot: 54% identical to NUOG_RICBR: NADH-quinone oxidoreductase subunit G (nuoG) from Rickettsia bellii (strain RML369-C)

KEGG orthology group: K00336, NADH dehydrogenase I subunit G [EC: 1.6.5.3] (inferred from 100% identity to rpa:RPA2944)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (691 amino acids)

>TX73_015255 NADH-quinone oxidoreductase subunit NuoG (Rhodopseudomonas palustris CGA009)
MIKIIVDGKEVEVPPEYTLLQACESAGAEIPRFCYHERLSIAGNCRMCLVELKGTPKPVA
SCAWGVRDCRPGPNGEPPEISTKSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQ
AMGYGVDQSRFAENKRAVEDKYLGVLVKTSMTRCIQCTRCVRFAAEICGVPEMGAIGRGE
DMEITTYLERALTSELQGNLVDICPVGALTSKPYAFAARPWELGKTQSVDVMDGVGSAIR
VDTRGREVMRILPRVNEAINEEWISDKTRHVVDGLRTQRLDRPYVREGGKLKPASWQQAF
AAIKAKLDGTSAKKIGAIAGDLAAVEEMFALKQLLAKLGSTNVAAQNVAAFDPKAGRASY
IFNPGIVGIEQADAVLIIGSDPRKEAAILNARIRKRWRASGMPIGVIGDQAELTYHYDYL
GAGTDTLNDLIAGKLGFAETLKNAKRPIILVGAAATARRDGAAILSLAAKLAADVGALDD
GWNGFAVLHPAASSVGALDIGFVPGAGGLGAAEMATAGGVDVLFSLGADEVKLPDGAFVV
YIGTHGDRGAHRADVILPGAAYTEKSGIYVNTEGRVQIAGRASFPPGDAREDWAILRALS
EALGAKLPYDSLAALRKALFAEVPHLMRVDQIEAGNPADLRKLASAGGSVEKTPFKPVIA
DFYMTNPIARASAVMAECSRLASGQLLTAAE