Protein Info for TX73_014550 in Rhodopseudomonas palustris CGA009

Annotation: 7-cyano-7-deazaguanine synthase QueC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 PF06508: QueC" amino acids 10 to 233 (224 residues), 226.8 bits, see alignment E=1e-71 TIGR00364: queuosine biosynthesis protein QueC" amino acids 10 to 226 (217 residues), 197 bits, see alignment E=1.2e-62

Best Hits

Swiss-Prot: 100% identical to QUEC_RHOPA: 7-cyano-7-deazaguanine synthase (queC) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

KEGG orthology group: K06920, queuosine biosynthesis protein QueC (inferred from 100% identity to rpt:Rpal_3150)

Predicted SEED Role

"Queuosine Biosynthesis QueC ATPase" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (237 amino acids)

>TX73_014550 7-cyano-7-deazaguanine synthase QueC (Rhodopseudomonas palustris CGA009)
MTDHSSDKTALVLFSGGQDSATCLAWALARFARVETIGFDYGQRHLIELECRARLLDGFR
AISDDWAAKLGDNHTLTIPTLAEISDTALTRDVAIAMGADGLPNTFVPGRNLIFLNFAAA
LAYRRGITDIVGGMCETDYSGYPDCRNDTIQALQTALSLGMARDITLHTPLMWRDKAATW
QLAQDLGGDALVDLIREDSHTCYLGERGARHDWGYGCGECPACRLRAKGWIEYASGI