Protein Info for TX73_014485 in Rhodopseudomonas palustris CGA009

Annotation: PLP-dependent aminotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 PF00392: GntR" amino acids 26 to 87 (62 residues), 56.8 bits, see alignment E=1.4e-19 PF00155: Aminotran_1_2" amino acids 164 to 410 (247 residues), 81.9 bits, see alignment E=5.5e-27

Best Hits

KEGG orthology group: K00375, GntR family transcriptional regulator / MocR family aminotransferase (inferred from 99% identity to rpt:Rpal_3136)

Predicted SEED Role

"Predicted transcriptional regulator of pyridoxine metabolism" in subsystem Pyridoxin (Vitamin B6) Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (496 amino acids)

>TX73_014485 PLP-dependent aminotransferase family protein (Rhodopseudomonas palustris CGA009)
MFKHSQLESVKAWVAHPAHAAMPLHARVQRAIRQLIVDGVLGAGKPLPASRALAQSLGVS
RDTIEVAYGQLHAEGFIERRVGSGSFVAEMTEFAPGRRLSQRDALHRNQAPKLSKRGTAM
FGSGGIREQLLPRPFVHGVPETRTFPLPLWERLERQVRKELGAQTLLHCDPQGTEPLRRA
IADYVNLERGARASADRVLVLTSSQQALSLCANMLLDPGDRVFIEDPAYYGARKAFDAAG
LECVPIPVDRQGLVVDQITAQPRRAKAVFLTPSHQFPTGATLALDRRLALIEWAARHQTW
IIEDDYDSEFHYAGKPTACVQGLDPHDRTVYIGTFTKSLFPGLRIGYVVLPPQLVKPMTV
ARTLLDGHSASMAQLTLARFMEGGHFGAHVRTMRGVYAQRLDVLVRLVRKYLSGFVEPRV
PVGGLQLPCVLTCDLAERTVVDAAQRVGIELLGLSGLQHARHGEAGFLMGFAAYTPLEIE
GAVKKLAKALRAAAKS