Protein Info for TX73_014395 in Rhodopseudomonas palustris CGA009

Annotation: MBL fold metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF12706: Lactamase_B_2" amino acids 52 to 235 (184 residues), 125.9 bits, see alignment E=1.6e-40 PF00753: Lactamase_B" amino acids 53 to 117 (65 residues), 27.5 bits, see alignment E=3e-10

Best Hits

KEGG orthology group: K06167, PhnP protein (inferred from 100% identity to rpa:RPA2779)

Predicted SEED Role

"Metal-dependent hydrolases of the beta-lactamase superfamily I; PhnP protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (267 amino acids)

>TX73_014395 MBL fold metallo-hydrolase (Rhodopseudomonas palustris CGA009)
MTLTLTILGSGSSAGVPRPALGWGAADPSNPKNRRLRCSLLAERITPEGGITRVLIDTSP
DLREQLISADVDHLDAVFLTHEHADQTHGIDDLRSVVMAMKRRIPVYLNQSTGEHVLYRF
AYCFKQAPGSSYPAILESREIEAGDSKTIAGAGGDLTLTAFLLQHGDIPALGYRIAGAAY
TPDVHDIPEQSFPALEGLDLWIIDGLRYKHHASHFNIETALKWINRFKPKRAVITNMHAD
IDYETLRKELPDGVVPGFDGMRLEIAG