Protein Info for TX73_013965 in Rhodopseudomonas palustris CGA009

Annotation: holo-ACP synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 146 TIGR00516: holo-[acyl-carrier-protein] synthase" amino acids 1 to 133 (133 residues), 91 bits, see alignment E=7.1e-30 TIGR00556: phosphopantetheine--protein transferase domain" amino acids 2 to 132 (131 residues), 71.8 bits, see alignment E=5.7e-24 PF01648: ACPS" amino acids 4 to 99 (96 residues), 64.3 bits, see alignment E=5e-22

Best Hits

Swiss-Prot: 100% identical to ACPS_RHOPA: Holo-[acyl-carrier-protein] synthase (acpS) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

KEGG orthology group: K00997, holo-[acyl-carrier protein] synthase [EC: 2.7.8.7] (inferred from 100% identity to rpa:RPA2695)

Predicted SEED Role

"Holo-[acyl-carrier protein] synthase (EC 2.7.8.7)" in subsystem Fatty Acid Biosynthesis FASII (EC 2.7.8.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (146 amino acids)

>TX73_013965 holo-ACP synthase (Rhodopseudomonas palustris CGA009)
MIIGIGSDLIDITRIAKVIERHGERFLDRVFTEAERAKAERRAKKSELVAATYAKRFAAK
EACSKALGTGIRQGVWWRDMGVVNLPGGRPTMVLTGGAKTRLDALTPPGMTARIDLSITD
EWPLAQAFVVISAIPAAAEQAVHTSS