Protein Info for TX73_013785 in Rhodopseudomonas palustris CGA009

Annotation: glutamine--fructose-6-phosphate transaminase (isomerizing)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01135: glutamine-fructose-6-phosphate transaminase (isomerizing)
  • amino acids 2 to 608 (607 residues), 794.6 bits, E=3e-243
• PF13522: GATase_6
  • amino acids 65 to 192 (128 residues), 74.8 bits, E=1e-24
• PF13537: GATase_7
  • amino acids 87 to 196 (110 residues), 52.9 bits, E=5.5e-18
• PF01380: SIS
  • amino acids 290 to 416 (127 residues), 99.9 bits, E=1.5e-32
  • amino acids 460 to 591 (132 residues), 91.4 bits, E=6.6e-30

Best Hits

Swiss-Prot: 80% identical to GLMS_BRADU: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (glmS) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K00820, glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC: 2.6.1.16] (inferred from 100% identity to rpt:Rpal_2934)

Predicted SEED Role

"Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)" in subsystem Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 2.6.1.16)

MetaCyc Pathways

• O-antigen building blocks biosynthesis (E. coli) (10/11 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis I (5/5 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis II (3/6 steps found)
• UDP-N-acetyl-D-galactosamine biosynthesis III (2/6 steps found)
• chitin biosynthesis (4/9 steps found)
• CMP-legionaminate biosynthesis I (2/10 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (12/33 steps found)
• superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis (5/24 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Glutamate metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.16

Protein Sequence (608 amino acids)

>TX73_013785 glutamine--fructose-6-phosphate transaminase (isomerizing) (Rhodopseudomonas palustris CGA009)
MCGIIGILGRGPVAEQLVDSLKRLEYRGYDSAGVATLEDGELVRRRAEGKLKNLEAVLKR
QPLAGHVGIGHTRWATHGKPNEANAHPHAASGVAVVHNGIIENFRELRDELEGGGATFAS
ETDTEVVAHLVNSFLVKGLSPQDAVKAALPRLRGAFALAFVFKGYDDLMIGARKGSPLAI
GYGDGEMYLGSDAIALAPLTDDISYLDDGDWVVLTHTTAEVRDAKGDVVKRDVMKSGASS
FVVDKANYRHFMAKEIHEQPEVVGHTLARYLDMASERIALPMKLPFDFKDVQHLSITACG
TANYAGYVAKYWFEQFARLPVEIDIASEFRYREAPLRSGDLAIFISQSGETADTLAALRY
AKEQGLHTLSVVNVPTSTIARESEVVMPTLAGPEIGVASTKAFTCQLTALAALAIAAGRA
RGTLTDADEAKLVHGLIELPRLMAAALTHEPQIERLARDISKAQDVLYLGRGTSYPLALE
GALKLKEISYIHAEGYAAGELKHGPIALIDEKMPVVVIAPYDRVFEKTVSNMQEVAARGG
RIILMTDAKGAEEATVDSMVTIMMPDMPAAFTPMVYAIPVQLLAYHTAVVMGTDVDQPRN
LAKSVTVE