Protein Info for TX73_013650 in Rhodopseudomonas palustris CGA009

Annotation: nitrogenase component 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00148: Oxidored_nitro
  • amino acids 73 to 467 (395 residues), 258.6 bits, E=4.8e-81

Best Hits

KEGG orthology group: K02586, nitrogenase molybdenum-iron protein alpha chain [EC: 1.18.6.1] (inferred from 100% identity to rpa:RPA2636)

MetaCyc: 78% identical to methylthio-alkane reductase catalytic subunit alpha (Rhodospirillum rubrum)

Predicted SEED Role

"Nitrogenase (molybdenum-iron) alpha chain (EC 1.18.6.1)" in subsystem Nitrogen fixation (EC 1.18.6.1)

MetaCyc Pathways

• nitrogen fixation I (ferredoxin) (1/1 steps found)

KEGG Metabolic Maps

• Nitrogen metabolism
• Tetrachloroethene degradation

Isozymes

Compare fitness of predicted isozymes for: 1.18.6.1

Use Curated BLAST to search for 1.18.6.1

Protein Sequence (502 amino acids)

>TX73_013650 nitrogenase component 1 (Rhodopseudomonas palustris CGA009)
MVLNLKTSSVETREQRLGTIIGWDGTASKLADESAFSRGDCGGCGTKARRVCELEGPFTQ
GSVCSEQMVECQAGNIRDAVLIQHSPIGCGAGQVIYNSIYRNGLAMRGLPVQNIRFISTN
LRERDMVYGGAEKLAEAIRLAVERHQPKAVFIATSCASGIIGDDIESVARTAEAEFGIPI
IPLHCEGFKSKHWSTGFDATQHGILRQIVRRNPDKRQDDLINVINLWGTDVFSPMLGELG
LRVNYVVDMATVEELAQMSEARATVSFCYTLGTYLATALEQEFGVEQIKAPQPYGFAGTD
AWLRELARVTGREAQAEDYIAREHARVKPLLDELRPKLKGLKGYVATGSAYSHGLIGVLR
EIGVEVDGSLVFHHDPVYDSEDPRQDSLGHLIENYGDVRHFTVGNRQQYQFYNLLQRVKP
DFIIIRHNGLAPLAARLGIPAIPLGDEHHALGYQGMVNLGESILAALQHRKFHKDIAKRV
SLPYKQSWLAQKDPFALARAAS