Protein Info for TX73_011535 in Rhodopseudomonas palustris CGA009

Annotation: conjugal transfer protein TraG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 667 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 43 to 64 (22 residues), see Phobius details amino acids 72 to 96 (25 residues), see Phobius details PF02534: T4SS-DNA_transf" amino acids 111 to 557 (447 residues), 333.4 bits, see alignment E=3.8e-103 PF10412: TrwB_AAD_bind" amino acids 172 to 537 (366 residues), 92.1 bits, see alignment E=5.3e-30 PF12696: TraG-D_C" amino acids 401 to 522 (122 residues), 99.9 bits, see alignment E=1.6e-32

Best Hits

KEGG orthology group: K03205, type IV secretion system protein VirD4 (inferred from 100% identity to rpa:RPA2235)

Predicted SEED Role

"Type IV secretion system protein VirD4" in subsystem Type 4 secretion and conjugative transfer or pVir Plasmid of Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (667 amino acids)

>TX73_011535 conjugal transfer protein TraG (Rhodopseudomonas palustris CGA009)
MSATKILWGQVLVVALIVLASVWGATQWTAWQLGYQTELGRPWFVLMGHPIYAPPAFFWW
WYFFDAYAPKIFYQGAVIASAGGFASIAVAVGMSVWRAREAKNVTTYGSARWATHGELRT
AKLLGDDGVILGRFHQRYLRHDGPEHVLCFAPTRSGKGVGLVIPTLLTWPGACIVHDIKG
ENFGLTAGWRNRFSHVLRFDPTDISSDAYNPLLEVRRGPSEVRDVQNIADILVDPEGALE
KRNHWEKTSHALLVGAILHVLYAEADKTLAGVANFLSDPRRPIDTTLRAMMTTPHLGDDG
VHPVVASAARELLNKSENERSGVLSTAMSFLGLYRDPVVARVTRRCDWRISDLVDRRDPV
TLYLIVPPSDISRTKPLIRLILNQVGRRLTEDLAAKGRRHRLLLMLDEFPALGRLDFFES
ALAFMAGYGIRSFLIAQSLNQIEKAYGPNNAILDNCHVRVSFATNDERTAKRVSDALGTA
TEIRDARNYAGHRLSPWLGHLMVSRQETARPLLTPGEIMQLPPSDAIVLVSGLFPVRATK
ARYYEDRQLKARLLPPPTEPTQREEVGAQSDDWSALAPLPFAPTAARTSGDDAIDGDADD
SANAGVRREPEIPAHEAIAPETPLPVREFDALDDEPDDDALRAQTLQARMRGMARQAALD
PDDGIVL