Protein Info for TX73_011320 in Rhodopseudomonas palustris CGA009

Annotation: xanthine dehydrogenase family protein molybdopterin-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 791 PF01315: Ald_Xan_dh_C" amino acids 36 to 155 (120 residues), 83.9 bits, see alignment E=1.5e-27 PF02738: MoCoBD_1" amino acids 173 to 419 (247 residues), 231.4 bits, see alignment E=1.4e-72 PF20256: MoCoBD_2" amino acids 447 to 720 (274 residues), 272.1 bits, see alignment E=9.8e-85

Best Hits

KEGG orthology group: K03520, carbon-monoxide dehydrogenase large subunit [EC: 1.2.99.2] (inferred from 100% identity to rpa:RPA2194)

Predicted SEED Role

"Carbon monoxide dehydrogenase large chain (EC 1.2.99.2)" in subsystem CO Dehydrogenase (EC 1.2.99.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.2.99.2

Use Curated BLAST to search for 1.2.99.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (791 amino acids)

>TX73_011320 xanthine dehydrogenase family protein molybdopterin-binding subunit (Rhodopseudomonas palustris CGA009)
MQDRPAIASLDTSLALHKFGVGQPVRRKEDETLLRGKGRYTDDCNLPGQFYAVMVRSPHP
HGIIRGIGTEAAKAMPGVCAIYTGADLASAGYAPFSSGLPLKSRDGTPLKQTHHGALPTD
KVRFVGEAVAYVVAKTLAQARDAAEAVELDIEPLPAVTDAEAAMQPGAPQLYDHIENNVA
LDYHFGDTAAVNAAFAAAAHVTTLDIENTRVAAVPMEPRVGLASYDQQNGRYTIQLPTQG
VSGNRNTLAKLLGVPTDKVRVLTGQVGGSFGMKNISYPEYICILHAAKTLGRPVKWTDER
STSFLSDSQGRGQQIRAELALDAGGRFLAIRLSGTGNLGAYITGVAPLPLSLNTGKNIGS
VYRTPLLSVDIKCVVTNVTLMGAYRGAGRPEANYFLERLIDRAADEMGIDRLTLRKRNFI
KPTQMPFTACSGVTYDSGDFAGVFGQALELSDYDGFAKRKKDARKAGKLRGIAVGSYLEV
TAPPNPELGKIVFEADGTVRLITGTLDYGQGHATPFAQVLSTFLGVPFERIRLEQGDSDI
VHTGNGTGGSRSITASGMAIVEASQKVIAKGKSAAAHLLETAEADIEFTDGRFTVAGTDR
SIGIMDLAQRLRGAELPEGVPASLDVDHTTEGVPSAFPNGCHVAEVEIDPDTGVTRVVRY
TAVNDFGTVVNPMIVAGQLHGGVAQGIGQALMEKVSYNADGQPITGSLQDYALPRAEDIP
LMTVGDHPVPAKTNPLGTKGCGEAGCAGSLATIVNAALDALKDYGVTTLDMPLTPEKVWR
AIHEAKAKTAA