Protein Info for TX73_011015 in Rhodopseudomonas palustris CGA009

Annotation: response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 707 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 268 to 284 (17 residues), see Phobius details amino acids 291 to 311 (21 residues), see Phobius details PF02518: HATPase_c" amino acids 446 to 563 (118 residues), 68.3 bits, see alignment E=7.6e-23 PF00072: Response_reg" amino acids 588 to 694 (107 residues), 64.4 bits, see alignment E=1e-21

Best Hits

KEGG orthology group: K02482, two-component system, NtrC family, sensor kinase [EC: 2.7.13.3] (inferred from 100% identity to rpa:RPA2135)

Predicted SEED Role

"Sensory kinase protein"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (707 amino acids)

>TX73_011015 response regulator (Rhodopseudomonas palustris CGA009)
MLTAQRDSLRLLRAILVASVVLPIALFSYASWLAYRTNEANADRQIDKTRDIITEHALKI
FESVQRSIAETAEIVRGMSDDEIRANEPALHERLKRLVGGSEQIKSMWIFDKTGRPLVNT
MQFPSPTPDLSDRDYFRIHLGKNTGLYVGRVLQPRPPFDGAPFFSVSRRRDASDGSFAGV
IQTSVLPDYFEGFYAKVGREDGSFASLVREDGAILARMPEIDGTDTAVKPDGIVGQAIRE
GHSEGRMTTVSSLDGVERRVAFRKLPSLPVYVFAGLETSAIRATWQAQMGAYLLVGLPAT
AALIAIVLLAIRRTQKLYEEADRRHIAENALKQSQRLESLGRLTGGVAHDFNNLLMVVGG
SVQRLRRRHSDLQDIRSFDMIDSAVAKGTALTRQLLSFSRRHNVAAKAVDLGDAVTKFAD
VLRQSVRSDIGIMIDPPAEPVVVMIDPNEFEIALLNLALNARDAMPDGGRITISIRTETL
KNFGPRKLTGTYAILSFADTGVGIPDDIRERIFEPFFTTKPVDRGTGLGLSQIYGFVQQS
SGAITVDSDLGRGTRFDLFLPLSAETLGLDEPTAELAPPQSGKPKTLLLVEDHPDVASVA
ADYAGQCGFTVVPANCAEAAVEVLNRRRDIDLVFSDIVMPGMSGLELARLIREHHPETPV
VLASGYSDRSASALSEGFALLQKPYTLDEMRAALTQALQSASDTAPV