Protein Info for TX73_010880 in Rhodopseudomonas palustris CGA009

Annotation: sigma 54-interacting transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 641 PF00989: PAS" amino acids 162 to 277 (116 residues), 62.6 bits, see alignment E=1.8e-20 TIGR00229: PAS domain S-box protein" amino acids 164 to 287 (124 residues), 69.9 bits, see alignment E=1.1e-23 PF08448: PAS_4" amino acids 169 to 282 (114 residues), 55.1 bits, see alignment E=4.3e-18 PF13426: PAS_9" amino acids 171 to 278 (108 residues), 58.2 bits, see alignment E=4.4e-19 PF08447: PAS_3" amino acids 183 to 271 (89 residues), 32 bits, see alignment E=6e-11 PF00158: Sigma54_activat" amino acids 321 to 488 (168 residues), 248.9 bits, see alignment E=1e-77 PF14532: Sigma54_activ_2" amino acids 322 to 488 (167 residues), 77.8 bits, see alignment E=5e-25 PF07728: AAA_5" amino acids 345 to 464 (120 residues), 33.4 bits, see alignment E=2.1e-11 PF00004: AAA" amino acids 345 to 481 (137 residues), 26.6 bits, see alignment E=3.7e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpa:RPA2111)

Predicted SEED Role

"Formate hydrogenlyase transcriptional activator" in subsystem Formate hydrogenase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (641 amino acids)

>TX73_010880 sigma 54-interacting transcriptional regulator (Rhodopseudomonas palustris CGA009)
MDLSSPSSFTATIDAPLRAAVFDSAVEAVLLVDPTLDQIVDANNAASALLGHDRDTLLQT
RFSALHGAQLPALVVFTQAVFAKGTYWTHALTPLHADGTQLRLEYAGKLLPYRGRSLLLL
TMSDLEQRRRRYVDAVADDYMRDGLPAWQRVERVFQDIERENQLILRAAGEGIYGVNAEG
KTTFVNPAAERMLGWSAEELVGKEMHAMVHHSHHDGRHYPGQQCPIYAAFRDGAVHTVDG
EVFWHKDGTPVWVEYTSTPIHDRSGGVVGAVVVFRDVNQRHEADEKLHAALAEVDRLRER
LQLENDYLQEEIRIETNPRGIIGQSEAIQTTLRQVKLVAPTAATVLITGESGTGKELIAR
AIHEASTRRDRPLIRVNCAAIPRELFESEFFGHARGAFTGAVRDRIGRFELADGGTLFLD
EVGEIPLELQSKLLRVLQEGNFERVGEERTRNVDVRLIAATNRDLKREVQRGHFREDLYF
RLSVFPIESVPLRDRREDIPLLAQHFLTNEARELKTELRLSQGDVRRLMRYDWPGNVREL
QNVIERATILAQNGRLRLDLPESAGSHASATSGRQKPDARPVVMTVADLRNLERDNIIAA
LRACKGKVFGDDGAAAMLDMKPTTLASRIKALGITSPRAQA