Protein Info for TX73_010785 in Rhodopseudomonas palustris CGA009

Annotation: FAD-dependent tricarballylate dehydrogenase TcuA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01266: DAO" amino acids 2 to 115 (114 residues), 28.2 bits, see alignment E=3.5e-10 PF12831: FAD_oxidored" amino acids 2 to 71 (70 residues), 28.3 bits, see alignment E=3e-10 PF03486: HI0933_like" amino acids 2 to 186 (185 residues), 28.1 bits, see alignment E=2.2e-10 TIGR02485: precorrin 3B synthase CobZ" amino acids 3 to 434 (432 residues), 757.3 bits, see alignment E=2.3e-232 PF13450: NAD_binding_8" amino acids 3 to 58 (56 residues), 29.1 bits, see alignment 2.4e-10 PF00890: FAD_binding_2" amino acids 3 to 403 (401 residues), 94.7 bits, see alignment E=1.9e-30

Best Hits

KEGG orthology group: K13796, tricarballylate dehydrogenase (inferred from 100% identity to rpa:RPA2093)

Predicted SEED Role

"TcuA: flavoprotein used to oxidize tricarballylate to cis-aconitate" in subsystem Tricarballylate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (434 amino acids)

>TX73_010785 FAD-dependent tricarballylate dehydrogenase TcuA (Rhodopseudomonas palustris CGA009)
MTVIGGGIAGLCAAIAARRGGAVVRLLEAAPRPLRGGNARHGRNFRLTHETPLDYVPDRY
TAEELRAELRSVTGDDTDRALTELLIERAHSIAGWLIDHGVHLQPPGTGVMPYSRRTAFP
LGGGKAMINALYASAERLGIAINYDSEVRSILRSEGGGWTINVRSAGADDPIRTRSVVVC
AGGAGADPAWLRANFGSTAEGWMVRGTPYADGRLLDLLIGAGGCAIGDPTTCHVVPVDAR
GPQFDGGIVTRITSIPLGLVVDRSGARIDVAGAGSQPTHYAKWGPRIADCPGQLAYLLLD
TRGLARAAPSALAPITAPSLGELAATLAIDPAALLQNIDDFNAAPANAARTIAVPPFFAY
PMRPGLTFVHYGIKVDATMRVVQADGRRHDDLFAAGMIMAANVLRRGYLAGLGITLSAVF
GQIAGEEAARHVRG